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CAS 141979-56-8

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1,6-DI-O-ACETYL-2,3-ISOPROPYLIDENE-D-RIBOSE

Description:
1,6-Di-O-acetyl-2,3-isopropylidene-D-ribose is a modified sugar derivative, specifically a ribose sugar that has undergone acetylation and protection of its hydroxyl groups. This compound features two acetyl groups at the 1 and 6 positions, which enhance its stability and solubility, making it useful in various chemical reactions and applications. The isopropylidene group at the 2 and 3 positions serves to protect the hydroxyl groups, preventing unwanted reactions during synthesis. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dichloromethane and acetone, but less soluble in water due to its hydrophobic modifications. It is primarily used in organic synthesis, particularly in the preparation of nucleosides and nucleotides, which are essential for biochemistry and molecular biology research. The presence of acetyl and isopropylidene groups allows for selective reactions, making it a valuable intermediate in the synthesis of more complex biomolecules.
Formula:C12H18O7
InChI:InChI=1/C12H18O7/c1-6(13)15-5-8-9-10(19-12(3,4)18-9)11(17-8)16-7(2)14/h8-11H,5H2,1-4H3
SMILES:CC(=O)OCC1C2C(C(OC(=O)C)O1)OC(C)(C)O2
Synonyms:
  • 1,5-Di-O-acetyl-2,3-O-isopropylidene-D-ribofuranose
  • 1,5-Di-O-acetyl-2,3-isopropylidene-D-ribose
  • 2,3-O-(1-methylethylidene)-D-Ribofuranose-1,5- diacetate
  • 1,5-di-O-acetyl-2,3-O-(1-methylethylidene)pentofuranose
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