CAS 1420367-28-7

Lp-PLA2-IN-1

CAS: 1420367-28-7

Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.

Formula: C₂₁H₁₇F₅N₄O₃

Purity: 99.60%

Color and Shape: White Solid

Molecular weight: 468.38

Ref: TM-T15782

Lp-PLA2-IN-1

CAS: 1420367-28-7

Lp-PLA2-IN-1

Formula: C₂₁H₁₇F₅N₄O₃

Purity: ≥98%

Molecular weight: 468.38

Ref: 54-BUP04279

Lp-PLA2-IN-1

CAS: 1420367-28-7

8-((3,5-Difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-1,2,3,4-tetrahydro-6H-pyrimido[1,6-a]pyrimidin-6-one

Formula: C₂₁H₁₇F₅N₄O₃

Purity: 99%

Molecular weight: 468.38

Ref: IN-DG764761

Lp-PLA2 -IN-1

CAS: 1420367-28-7

Lp-PLA2-IN-1 is a small molecule inhibitor, which is derived from chemical synthesis, designed to specifically inhibit the activity of lipoprotein-associated phospholipase A2 (Lp-PLA2). This enzyme is involved in the hydrolysis of oxidized phospholipids on low-density lipoproteins (LDL), leading to the production of pro-inflammatory mediators. The mode of action involves the selective binding to the active site of Lp-PLA2, thus preventing the enzyme from catalyzing its reaction and subsequently reducing the formation of pro-inflammatory lysophosphatidylcholine and oxidized free fatty acids.

Formula: C₂₁H₁₇F₅N₄O₃

Purity: Min. 95%

Molecular weight: 468.38 g/mol

Ref: 3D-VGC36728