CAS 1422284-17-0

2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1-ethyl 9-(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)

Description:

2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, with the CAS number 1422284-17-0, is a complex organic compound characterized by its unique structural features, including multiple oxygen atoms and a phosphorus atom integrated into its backbone. This compound exhibits properties typical of phosphonates, such as potential reactivity with nucleophiles and the ability to form stable complexes with metal ions. The presence of the purine derivative in its structure suggests biological relevance, possibly indicating its role in biochemical pathways or as a pharmaceutical agent. The ester functional groups imply that it may undergo hydrolysis, which can influence its stability and solubility in various solvents. Additionally, the compound's stereochemistry, indicated by the (1R) configuration, may affect its interaction with biological targets, enhancing its specificity and efficacy. Overall, this compound's intricate structure and functional groups suggest potential applications in medicinal chemistry, particularly in drug design or as a biochemical probe. However, detailed studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₁₈H₂₈N₅O₁₀P·C₄H₄O₄

SMILES: C([C@H](OCP(OCOC(OC(C)C)=O)(OCOC(OCC)=O)=O)C)N1C=2C(N=C1)=C(N)N=CN2.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide
• 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1-ethyl 9-(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)

DEC-POC PMPA

CAS: 1422284-17-0

Formula: C₂₂H₃₂N₅O₁₄P

Purity: 95%

Molecular weight: 621.4883

Ref: IN-DA01Q8Z6

Tenofovir Disoproxil Impurity EOC-POCPMPA Fumarate

CAS: 1422284-17-0

Formula: C₁₈H₂₈N₅O₁₀P·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 505.43 116.07

Ref: 4Z-T-028

DEC-POC PMPA

Controlled Product

CAS: 1422284-17-0

Formula: C₁₈H₂₈N₅O₁₀P·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 621.49

Ref: TR-D209905

Dec-poc pmpa

CAS: 1422284-17-0

Dec-poc pmpa is an oral prodrug that exhibits potent antiviral activity against HIV. It is rapidly converted to its active form, tenofovir alafenamide hemifumarate, in the presence of hydrochloric acid. Dec-poc pmpa has excellent pharmacokinetic properties, resulting in sustained plasma levels and enhanced bioavailability compared to other pharmaceutical preparations of tenofovir. This prodrug undergoes a phase transfer reaction in the body, allowing for efficient conversion to the active antiretroviral agent. Additionally, Dec-poc pmpa has been formulated to minimize impurities and contains an acid-binding agent to reduce potential renal biomarkers associated with tenofovir administration. Its mechanism of action involves inhibiting viral replication by targeting adenine residues in viral DNA synthesis.

Formula: C₂₂H₃₂N₅O₁₄P

Purity: Min. 95%

Molecular weight: 621.5 g/mol

Ref: 3D-XGC28417