CAS 142253-56-3

1-Boc-azetidine-3-ylmethanol

Description:

1-Boc-azetidine-3-ylmethanol is a chemical compound characterized by its azetidine ring structure, which is a four-membered saturated heterocycle containing one nitrogen atom. The "Boc" (tert-butyloxycarbonyl) group is a common protecting group in organic synthesis, particularly for amines, and it enhances the stability and solubility of the compound. The presence of the hydroxymethyl (-CH2OH) group at the 3-position of the azetidine ring indicates that this compound has potential applications in medicinal chemistry and organic synthesis, particularly in the development of pharmaceuticals. The compound is typically a white to off-white solid and is soluble in polar organic solvents. Its reactivity can be influenced by the Boc group, which can be removed under acidic conditions to yield the free amine, allowing for further functionalization. Overall, 1-Boc-azetidine-3-ylmethanol serves as a versatile intermediate in the synthesis of more complex molecules.

Formula: C₉H₁₇NO₃

Synonyms:

• Tert-Butyl 3-(Hydroxymethyl)azetidine-1-Carboxylate
• 3-Hydroxymethyl-azetidine-1-Carboxylic acid Tert-Butyl ester
• 1-Boc-azetidine-3-yl methanol
• 3-(Hydroxymethyl)azetidine-1-carboxylate
• 1-Boc-3-hydroxymethylazetidine
• 1-Boc-3-azetidinemethanol

1-(tert-Butoxycarbonyl)-3-azetidinemethanol

CAS: 142253-56-3

Formula: C₉H₁₇NO₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to lump

Molecular weight: 187.24

Ref: 3B-B3992

1-Azetidinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester

CAS: 142253-56-3

Formula: C₉H₁₇NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 187.2362

Ref: IN-DA001I2C

tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate

CAS: 142253-56-3

tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate

Formula: C₉H₁₇NO₃

Purity: 98%

Color and Shape: Light red. Solid

Molecular weight: 187.23617

Ref: 54-OR308030

1-Boc-azetidine-3-yl-methanol

CAS: 142253-56-3

Formula: C₉H₁₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 187.239

Ref: 10-F076509

1-Boc-azetidine-3-yl-methanol

CAS: 142253-56-3

Stable under physiological and chemical conditions, 1-Boc-azetidine-3-yl-methanol is a linker that forms permanent bonds in conjugates, particularly in antibody-drug conjugates (ADCs) and as a linker in PROTAC (PROteolysis TArgeting Chimera) molecules for targeted protein degradation. It is also a versatile chemical intermediate used to synthesize complex organic molecules, particularly in pharmaceuticals, agrochemicals, and research chemicals.

Formula: C₉H₁₇NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 187.24 g/mol

Ref: 3D-FB11553

1-Boc-azetidine-3-yl-methanol

CAS: 142253-56-3

1-Boc-Azetidine-3-yl-methanol

Formula: C₉H₁₇NO₃

Purity: 98%

Molecular weight: 187.24

Ref: IN-DG27079