CAS 142273-20-9: Kenpaullone

Description: Kenpaullone is a synthetic compound that belongs to the class of small molecules known as kinase inhibitors. It is primarily recognized for its ability to inhibit cyclin-dependent kinases (CDKs), which play a crucial role in cell cycle regulation and are implicated in various cancers. The molecular structure of Kenpaullone features a unique arrangement that allows it to interact effectively with the ATP-binding site of CDKs, thereby blocking their activity. This inhibition can lead to cell cycle arrest and has potential therapeutic implications in cancer treatment. Kenpaullone is also noted for its selectivity towards certain CDK isoforms, making it a valuable tool in both research and drug development. Additionally, it has been studied for its effects on other cellular pathways, contributing to its profile as a multi-targeted agent. As with many chemical substances, safety and handling precautions are essential due to its bioactive nature. Overall, Kenpaullone represents a significant interest in the field of medicinal chemistry and cancer therapeutics.

Formula: C₁₆H₁₁BrN₂O

InChI: InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)

InChI key: InChIKey=QQUXFYAWXPMDOE-UHFFFAOYSA-N

SMILES: O=C1NC=2C=CC=CC2C=3NC=4C=CC(Br)=CC4C3C1

Synonyms:

• 8-Bromo-7,12-Dihydro-Indolo[3,2-D][1]-Benzazepin-6(5H)-One
• 9-Bromo-7,12-Dihydro-Indolo[3,2-D][1]Benzazepin-6(5H)-One
• 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704
• 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
• 9-Bromopaullone
• Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-
• Nsc-664704
• Kenpaullone

Kenpaullone

CAS: 142273-20-9

• Formula: C₁₆H₁₁BrN₂O
• Purity: >97.0%(HPLC)
• Color and Shape: Light yellow to Brown powder to crystal
• Molecular weight: 327.18

Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-

CAS: 142273-20-9

• Formula: C₁₆H₁₁BrN₂O
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 327.1753

Kenpaullone

CAS: 142273-20-9

• Formula: C₁₆H₁₁BrN₂O
• Molecular weight: 327.18

9-Bromo-7,12-Dihydrobenzo[2,3]Azepino[4,5-B]Indol-6(5H)-One

CAS: 142273-20-9

• Purity: 99%
• Molecular weight: 327.18g/mol

KenPaullone

CAS: 142273-20-9

• Purity: 98%
• Molecular weight: 327.18g/mol

KenPaullone

CAS: 142273-20-9

KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell …

• Formula: C₁₆H₁₁BrN₂O
• Purity: 97.14% - 98.99%
• Color and Shape: Tan Solid
• Molecular weight: 327.18

Kenpaullone

CAS: 142273-20-9

• Purity: >95%
• Molecular weight: 327.1809997558594

Kenpaullone

CAS: 142273-20-9

Inhibitor of glycogen synthase 3 (GSK-3) and cyclin-dependent kinases CDK1, CDK2 and CDK5. Kenpaullone can …

• Formula: C₁₆H₁₁BrN₂O
• Purity: Min. 95%
• Color and Shape: Yellow To Dark Yellow Solid
• Molecular weight: 326.00548

Kenpaullone

CAS: 142273-20-9

Applications The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. …

• Formula: C₁₆H₁₁BrN₂O
• Color and Shape: Neat
• Molecular weight: 327.18