CAS 1426944-49-1

Formula: C25H28ClN3O

InChI: InChI=1S/C25H28ClN3O/c1-29(17-18-8-3-2-4-9-18)15-7-14-27-25(30)19-12-13-23-21(16-19)24(26)20-10-5-6-11-22(20)28-23/h2-4,8-9,12-13,16H,5-7,10-11,14-15,17H2,1H3,(H,27,30)

InChI key: ZCALMLVWZSQGGR-UHFFFAOYSA-N

SMILES: CN(CCCNC(=O)C1=CC2=C(C=C1)N=C3CCCCC3=C2Cl)CC4=CC=CC=C4

HBX 19818

CAS: 1426944-49-1

HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).

Formula: C₂₅H₂₈ClN₃O

Purity: 97.71%

Color and Shape: Solid

Molecular weight: 421.962

Ref: TM-T15464

HBX 19818

CAS: 1426944-49-1

HBX 19818

Formula: C₂₅H₂₈ClN₃O

Purity: ≥95%

Molecular weight: 421.96

Ref: 54-BUP08712

HBX 19818

CAS: 1426944-49-1

Formula: C₂₅H₂₈ClN₃O

Purity: 98%

Molecular weight: 421.9623

Ref: IN-DA00A11V

HBX 19818

CAS: 1426944-49-1

N-(3-(Benzyl(methyl)amino)propyl)-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide

Formula: C₂₅H₂₈ClN₃O

Purity: 98%

Molecular weight: 421.96

Ref: IN-DG630266

HBX 19818

CAS: 1426944-49-1

HBX 19818 is a synthetic molecule that has been shown to inhibit mutant FLT3. This leads to the inhibition of the proteolytic cleavage of pro-apoptotic proteins, such as BID and BAX, in cancer cells. HBX 19818 also inhibits the activity of the protein kinase domain, which is involved in cellular signaling pathways that regulate cell proliferation and survival. In addition, HBX 19818 induces apoptosis in ba/f3 cells through activation of caspase 3 and 9. HBX 19818 has also been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis in vitro.

Formula: C₂₅H₂₈ClN₃O

Purity: Min. 95%

Molecular weight: 421.96 g/mol

Ref: 3D-BHC94449