CAS 142846-71-7

galanin (1-13)-bradykinin (2-9) amide

Description:

Galanin (1-13)-bradykinin (2-9) amide is a synthetic peptide that combines elements of the neuropeptide galanin and the vasoactive peptide bradykinin. This compound is characterized by its specific amino acid sequence, which influences its biological activity and receptor interactions. Galanin is known for its role in various physiological processes, including modulation of neurotransmission, pain perception, and regulation of food intake, while bradykinin is primarily involved in vasodilation and inflammatory responses. The amide form of this peptide suggests that it has a terminal amine group, which can enhance its stability and bioactivity. The CAS number 142846-71-7 uniquely identifies this compound in chemical databases, facilitating research and application in pharmacology and biochemistry. Overall, galanin (1-13)-bradykinin (2-9) amide represents a fascinating area of study due to its potential therapeutic implications in pain management and neurobiology.

Formula: C₁₀₇H₁₅₃N₂₇O₂₆

InChI: InChI=1/C107H153N27O26/c1-57(2)42-70(123-93(147)71(43-58(3)4)124-95(149)74(47-64-33-35-66(138)36-34-64)121-86(141)52-115-91(145)60(7)118-100(154)78(55-135)128-98(152)77(49-84(109)139)125-94(148)72(44-59(5)6)127-103(157)89(61(8)137)130-99(153)76(119-85(140)50-108)48-65-51-114-68-27-16-15-26-67(65)68)92(146)117-54-88(143)131-38-20-31-82(131)105(159)134-41-21-32-83(134)106(160)133-40-18-29-80(133)101(155)116-53-87(142)120-73(45-62-22-11-9-12-23-62)96(150)129-79(56-136)104(158)132-39-19-30-81(132)102(156)126-75(46-63-24-13-10-14-25-63)97(151)122-69(90(110)144)28-17-37-113-107(111)112/h9-16,22-27,33-36,51,57-61,69-83,89,114,135-138H,17-21,28-32,37-50,52-56,108H2,1-8H3,(H2,109,139)(H2,110,144)(H,115,145)(H,116,155)(H,117,146)(H,118,154)(H,119,140)(H,120,142)(H,121,141)(H,122,151)(H,123,147)(H,124,149)(H,125,148)(H,126,156)(H,127,157)(H,128,152)(H,129,150)(H,130,153)(H4,111,112,113)/t60-,61+,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,89-/m0/s1

Synonyms:

• H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2
• M35

Galanin (1-13)-Bradykinin (2-9) amide

CAS: 142846-71-7

The galanin antagonist M35, which binds with high specificity and affinity to galanin binding sites, has been administered to rats to test the functional consequences of the galanin receptor blockade in a spatial learning task. The results suggest that galanin antagonists might provide a new principle in the treatment of dementia and related disorders. M35 (but not M40 or C7) ameliorated cerulein-induced acute pancreatitis in mice.

Formula: C₁₀₇H₁₅₃N₂₇O₂₆

Purity: 97.5%

Color and Shape: White Powder

Molecular weight: 2233.56

Ref: 01-4020106

Galanin Receptor Ligand M35

CAS: 142846-71-7

M35, a galanin(1-13)-bradykinin(2-9) amide, acts as a galanin antagonist in rats and inhibits mouse pancreatic islets.

Formula: C₁₀₇H₁₅₃N₂₇O₂₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 2233.6

Ref: TM-TP1662

M35

CAS: 142846-71-7

Please enquire for more information about M35 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₀₇H₁₅₃N₂₇O₂₆

Purity: Min. 95%

Molecular weight: 2,233.53 g/mol

Ref: 3D-FM73474