CAS 143-67-9: Vinblastine sulfate

Description:Vinblastine sulfate is a potent alkaloid derived from the periwinkle plant, Vinca rosea, and is primarily used in chemotherapy for treating various types of cancer, including Hodgkin's lymphoma and testicular cancer. It functions as a mitotic inhibitor, disrupting the process of cell division by binding to tubulin, which prevents the formation of microtubules necessary for mitosis. This action ultimately leads to cell cycle arrest and apoptosis in rapidly dividing cancer cells. Vinblastine sulfate is typically administered intravenously and is known for its side effects, which can include nausea, vomiting, hair loss, and bone marrow suppression. The compound is a white to off-white powder, soluble in water and slightly soluble in alcohol, with a molecular formula that reflects its complex structure. Due to its significant therapeutic effects and potential toxicity, vinblastine sulfate is used under strict medical supervision, and its dosage must be carefully managed to minimize adverse effects while maximizing its anticancer efficacy.

Formula:C₄₆H₅₈N₄O₉·H₂O₄S

InChI:InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

InChI key:InChIKey=KDQAABAKXDWYSZ-PNYVAJAMSA-N

SMILES:O=C(OC1C(O)(C(=O)OC)C2N(C3=CC(OC)=C(C=C3C42CCN5CC=CC1(CC)C54)C6(C(=O)OC)C=7NC=8C=CC=CC8C7CCN9CC(CC(O)(C9)CC)C6)C)C.O=S(=O)(O)O

Synonyms:
(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate (1:1)
(2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
(2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.
29060Le
2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv.
Alkaban-AQ
NSC 49842
See more synonyms
VLB monosulfate
Velban
Velbe
Velsar
Vinblastin Sulfate
Vinblastine Sulphate
Vinblastine sulfate salt
Vincaleucoblastine sulfate
Vincaleukoblastine Sulfate Salt
Vincaleukoblastine sulfate
Vincaleukoblastine, sulfate (1:1) (salt)

Found 15 products.

Product data	Purity	Price range	Estimated delivery
Vinblastine sulfate CRS REF: 41-V0300000CAS: 143-67-9	- - -	115.00 €	Thu 24 Apr 25
Vinblastine Sulfate REF: 45-1713004CAS: 143-67-9	- - -	972.00 €	Fri 25 Apr 25
vincaleukoblastine,sulfate(1:1) REF: IN-DA003AJNCAS: 143-67-9	97%	92.00 €~507.00 €	Mon 28 Apr 25
Vinblastine Sulfate (Vincristine EP Impurity H Sulfate) REF: 4Z-V-261CAS: 143-67-9	- - -	To inquire	Tue 29 Apr 25
Vinblastine sulfate REF: 54-BUP05992CAS: 143-67-9	≥98%	105.00 €~158.00 €	Tue 29 Apr 25
Vinblastine sulfate REF: 7W-GA7194CAS: 143-67-9	≥ 97.0%	42.00 €~437.00 €	Tue 29 Apr 25
Vinblastine sulfate, 96.0-102.0% REF: AC-20345CAS: 143-67-9	96.0-102.0%	To inquire	Tue 29 Apr 25
Vinblastine sulfate REF: BP-BP1437CAS: 143-67-9	95%~99%	53.00 €~326.00 €	Tue 29 Apr 25
Vinblastine sulfate REF: TM-T1668CAS: 143-67-9	97.81% - 99.38%	55.00 €~96.00 €	Mon 05 May 25
Vinblastine Sulfate RS REF: 2K-1126000021CAS: 143-67-9	- - -	To inquire	Tue 06 May 25
Vinblastine Sulfate REF: TR-V314000CAS: 143-67-9	- - -	94.00 €~241.00 €	Tue 06 May 25
Vinblastine sulfate REF: 3D-FV28694CAS: 143-67-9	Min. 80 Area-%	153.00 €~2,432.00 €	Wed 07 May 25
Vinblastine sulfate, 96% REF: 3D-BV179887CAS: 143-67-9	Min. 96 Area-%	175.00 €~928.00 €	Wed 07 May 25
Vinblastine Sulphate-d3 REF: TR-V314006CAS: 143-67-9	- - -	284.00 €~1,861.00 €	Thu 15 May 25
Vinblastine-d6 Sulfate REF: TR-V314001CAS: 143-67-9	- - -	11,848.00 €	Tue 10 Jun 25