CAS 143-67-9

Vinblastine sulfate

Description:

Vinblastine sulfate is a potent alkaloid derived from the periwinkle plant, Vinca rosea, and is primarily used in chemotherapy for treating various types of cancer, including Hodgkin's lymphoma and testicular cancer. It functions as a mitotic inhibitor, disrupting the process of cell division by binding to tubulin, which prevents the formation of microtubules necessary for mitosis. This action ultimately leads to cell cycle arrest and apoptosis in rapidly dividing cancer cells. Vinblastine sulfate is typically administered intravenously and is known for its side effects, which can include nausea, vomiting, hair loss, and bone marrow suppression. The compound is a white to off-white powder, soluble in water and slightly soluble in alcohol, with a molecular formula that reflects its complex structure. Due to its significant therapeutic effects and potential toxicity, vinblastine sulfate is used under strict medical supervision, and its dosage must be carefully managed to minimize adverse effects while maximizing its anticancer efficacy.

Formula:C₄₆H₅₈N₄O₉·H₂O₄S

InChI:InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

InChI key:InChIKey=KDQAABAKXDWYSZ-PNYVAJAMSA-N

SMILES:S(=O)(=O)(O)O.C(C)[C@@]12[C@]3([C@@]4([C@]([C@](C(OC)=O)(O)[C@@H]1OC(C)=O)(N(C)C=5C4=CC(=C(OC)C5)[C@]6(C(OC)=O)C7=C(C=8C(N7)=CC=CC8)CC[N@@]9C[C@](C6)(C[C@](CC)(O)C9)[H])[H])CCN3CC=C2)[H]

Synonyms:

(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
(2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate (1:1)
(2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine
(2Alpha,3Alpha,4Alpha,5Beta,19Beta)-Vincaleukoblastine Sulfate
1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.
29060Le
2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv.
Alkaban-AQ
NSC 49842
VLB monosulfate
Velban
Velbe
Velsar
Vinblastin Sulfate
Vinblastine Sulphate
Vinblastine sulfate salt
Vincaleucoblastine sulfate
Vincaleukoblastine Sulfate Salt
Vincaleukoblastine sulfate
See more synonyms

Purity (%)

100

Found 18 products.

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VINBLASTINE SULFATE CRS
CAS:
- 143-67-9
VINBLASTINE SULFATE CRS
Formula:C₄₆H₆₀N₄O₁₃S
Color and Shape:Powder
Molecular weight:909.0526
Ref: 41-V0300000
5mg
132.00€
VAT not included
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Vinblastine Sulfate
CAS:
- 143-67-9
Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi
Formula:C₄₆H₅₈N₄O₉·H₂SO₄
Color and Shape:White Light Yellow Powder
Molecular weight:908.38776
Ref: 45-1713004
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Vinblastine sulfate
CAS:
- 143-67-9
Vinblastine sulfate
Formula:C₄₆H₅₈N₄O₉·H₂SO₄
Purity:≥95%
Molecular weight:909.06
Ref: 54-BUP05992
5mg
80.00€
VAT not included
10mg
85.00€
VAT not included
25mg
98.00€
VAT not included
50mg
127.00€
VAT not included
100mg
147.00€
VAT not included
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Vinblastine (sulfate)
CAS:
- 143-67-9
Formula:C₄₆H₆₀N₄O₁₃S
Purity:99%
Color and Shape:Solid
Molecular weight:909.0526
Ref: IN-DA003AJN
1mg
46.00€
VAT not included
5mg
57.00€
VAT not included
10mg
72.00€
VAT not included
50mg
87.00€
VAT not included
100mg
116.00€
VAT not included
250mg
192.00€
VAT not included
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Vinblastine sulfate
CAS:
- 143-67-9
Formula:C₄₆H₆₀N₄O₁₃S
Purity:≥ 97.0%
Color and Shape:White to off-white powder
Molecular weight:909.06
Ref: 7W-GA7194
1mg
44.00€
VAT not included
5mg
72.00€
VAT not included
10mg
125.00€
VAT not included
25mg
255.00€
VAT not included
50mg
459.00€
VAT not included
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Vinblastine Sulfate (Vincristine EP Impurity H Sulfate, Vindesine EP Impurity B Sulfate)
CAS:
- 143-67-9
Formula:C₄₆H₅₈N₄O₉·H₂SO₄
Color and Shape:White To Off-White Solid
Molecular weight:810.99 98.07
Ref: 4Z-V-261
5mg
To inquire
100mg
To inquire
10mg
343.00€
VAT not included
25mg
436.00€
VAT not included
50mg
623.00€
VAT not included
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Vinblastine sulfate
CAS:
- 143-67-9
Formula:C₄₆H₆₀N₄O₁₃S
Purity:95%~99%
Molecular weight:909.061
Ref: BP-BP1437
20mg
53.00€
VAT not included
100mg
107.00€
VAT not included
1000mg
326.00€
VAT not included
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Vinblastine sulfate
CAS:
- 143-67-9
Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((5S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate
Formula:C₄₆H₆₀N₄O₁₃S
Purity:99%
Molecular weight:909.05
Ref: IN-DG31931
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Vinblastine sulfate
CAS:
- 143-67-9
Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
Formula:C₄₆H₅₈N₄O₉·H₂SO₄
Purity:97.81% - 99.98%
Color and Shape:White Powder
Molecular weight:909.06
Ref: TM-T1668
5mg
52.00€
VAT not included
10mg
56.00€
VAT not included
1mL*10mM (DMSO)
65.00€
VAT not included
25mg
66.00€
VAT not included
50mg
87.00€
VAT not included
100mg
90.00€
VAT not included
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Vinblastine Sulfate RS
CAS:
- 143-67-9
Color and Shape:White To Slightly Yellow Solid Powder
Ref: 2K-112600002
50mg
To inquire
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Vinblastine Sulphate-d3
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 143-67-9
Applications Vinblastine Sulphate-d3 is labelled salt of Vinblastine, which is an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly.
References Lu, C., et al.: Cancer Research, 39, 3575 (1979), Gobbi, P.G., et al.: J. Clin. Oncol., 14, 527 (1996), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs. Excip., 21, 611 (1992),
Formula:C₄₆H₅₅D₃N₄O₉·xH₂SO₄
Color and Shape:Neat
Molecular weight:813.999808
Ref: TR-V314006
1mg
259.00€
VAT not included
10mg
1,651.00€
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Vinblastine Sulfate (10 mg/mL in DMSO)
CAS:
- 143-67-9
Formula:C₄₆H₅₈N₄O₉·H₂O₄S
Color and Shape:Single Solution
Molecular weight:909.05
Ref: TR-KIT5379
1x1ml
492.00€
VAT not included
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Vinblastine sulfate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 143-67-9
Disrupts microtubule assembly; anti-cancer agent
Formula:C₄₆H₆₀N₄O₁₃S
Purity:Min. 80 Area-%
Color and Shape:White Powder
Molecular weight:909.05 g/mol
Ref: 3D-FV28694
250mg
282.00€
VAT not included
500mg
391.00€
VAT not included
1g
596.00€
VAT not included
2g
1,005.00€
VAT not included
5g
2,302.00€
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Vinblastine sulfate, 96%
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 143-67-9
Vinblastine sulfate, 96%, is a chemotherapeutic agent, which is a semi-synthetic derivative of natural alkaloids extracted from the Madagascar periwinkle plant, Catharanthus roseus. This compound functions through the disruption of microtubule formation by binding to tubulin, effectively inhibiting mitosis. By preventing the assembly of microtubules, vinblastine sulfate interferes with the metaphase stage of cell division, leading to cell cycle arrest and subsequent apoptosis of rapidly dividing cancer cells.
Formula:C₄₆H₆₀N₄O₁₃S
Purity:Min. 96 Area-%
Color and Shape:Powder
Molecular weight:909.05 g/mol
Ref: 3D-BV179887
250mg
457.00€
VAT not included
500mg
645.00€
VAT not included
1g
894.00€
VAT not included
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Vinblastine-d6 Sulfate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 143-67-9
Formula:C₄₆D₆H₅₂N₄O₉·H₂SO₄
Color and Shape:Neat
Molecular weight:915.09
Ref: TR-V314001
100mg
10,511.00€
VAT not included
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Vinblastine Sulfate
CAS:
- 143-67-9
Formula:C₄₆H₅₈N₄O₉·H₂O₄S
Color and Shape:Neat
Molecular weight:909.05
Ref: TR-V314000
5mg
86.00€
VAT not included
10mg
116.00€
VAT not included
25mg
214.00€
VAT not included
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vinblastine Sulfate
CAS:
- 143-67-9
Formula:C₄₆H₅₈N₄O₉H₂SO₄
Molecular weight:810.99 : 98.07
Ref: ST-EA-CP-V330025
10mg
To inquire
25mg
To inquire
50mg
To inquire
100mg
To inquire
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Vinblastine Sulfate RS
CAS:
- 143-67-9
Color and Shape:White To Slightly Yellow Solid Crystals To Powder
Ref: 2K-1126000021
50mg
Discontinued
Request information
Discontinued product