CAS 1430213-30-1

Formula: C15H9F4N5OS

InChI: InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)

InChI key: WMCOYUSJXXCHFH-UHFFFAOYSA-N

SMILES: C1=CC(=C(C=C1NC(=O)NC2=NN=C(S2)C3=CC=NC=C3)C(F)(F)F)F

ML216

CAS: 1430213-30-1

ML216

Formula: C₁₅H₉F₄N₅OS

Purity: ≥95%

Molecular weight: 383.32

Ref: 54-BUP06162

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

CAS: 1430213-30-1

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

Formula: C₁₅H₉F₄N₅OS

Purity: 98+%

Molecular weight: 383.32

Ref: 54-PC108707

ML216

CAS: 1430213-30-1

Formula: C₁₅H₉F₄N₅OS

Purity: %

Color and Shape: Solid

Molecular weight: 383.3235

Ref: IN-DA009CDG

ML216

CAS: 1430213-30-1

ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).

Formula: C₁₅H₉F₄N₅OS

Purity: 98.12%

Color and Shape: Yellow Solid

Molecular weight: 383.323

Ref: TM-T5413

ML216

CAS: 1430213-30-1

1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea

Formula: C₁₅H₉F₄N₅OS

Purity: 98+%

Molecular weight: 383.32

Ref: IN-DG630270

1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea

CAS: 1430213-30-1

Purity: 98+%

Molecular weight: 383.3200073

Ref: 10-F870102

ML-216

Controlled Product

CAS: 1430213-30-1

Applications ML-216 is a small molecule inhibitor of Bloom (BLM) helicase.
References Rosenthal, A., et al.: Bioorg. Med. Chem. Lett., 23, 5660 (2013); Nguyen, G., et al.: Chem. Biol., 20, 55(2013)

Formula: C₁₅H₉F₄N₅OS

Color and Shape: Neat

Molecular weight: 383.324

Ref: TR-M425095

ML216

CAS: 1430213-30-1

ML216 is a chemotherapeutic drug that inhibits the repair mechanism of prostate cancer cells. It binds to leukocyte antigen (LFA-1) on the surface of tumor cells, and blocks the activity of suppressor genes that regulate the growth and development of these cells. ML216 has been shown to be active against prostate cancer cell lines in vitro and in vivo studies. This drug also has membrane permeability and anticancer activity.

Formula: C₁₅H₉F₄N₅OS

Purity: Min. 95%

Molecular weight: 383.32 g/mol

Ref: 3D-FHC21330