CAS 1431411-60-7

Thieno[3,2-d]pyriMidine-6-carboxaMide, 4-[4-[2-[(2,2-diMethyl-1-oxopropyl)aMino]ethyl]-1-piperidinyl]-

Description:

Thieno[3,2-d]pyrimidine-6-carboxamide, 4-[4-[2-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]-1-piperidinyl]- is a synthetic organic compound characterized by its unique bicyclic structure, which incorporates a thieno and pyrimidine moiety. This compound features a carboxamide functional group, contributing to its potential solubility and reactivity. The presence of a piperidine ring and a dimethyl-1-oxopropyl side chain suggests that it may exhibit significant biological activity, possibly as a pharmaceutical agent. The molecular structure indicates potential interactions with biological targets, making it of interest in medicinal chemistry. Its CAS number, 1431411-60-7, allows for precise identification and retrieval of information regarding its properties, synthesis, and applications. As with many compounds in this class, understanding its physicochemical properties, such as solubility, stability, and reactivity, is crucial for evaluating its potential uses in drug development or other chemical applications.

Formula: C₁₉H₂₇N₅O₂S

Synonyms:

• Inhibitor,Sirtuin,SIRT IN 1,SIRTIN1,inhibit
• 4-[4-[2-(2,2-dimethylpropanoylamino)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxamide
• 4-[4-[2-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]-1-piperidinyl]-Thieno[3,2-d]pyrimidine-6-carboxamide
• SIRT-IN-1
• Thieno[3,2-d]pyriMidine-6-carboxaMide, 4-[4-[2-[(2,2-diMethyl-1-oxopropyl)aMino]ethyl]-1-piperidinyl]-

SIRT-IN-1

CAS: 1431411-60-7

SIRT-IN-1

Formula: C₁₉H₂₇N₅O₂S

Purity: ≥95%

Molecular weight: 389.52

Ref: 54-BUP12631

SIRT-IN-1

CAS: 1431411-60-7

4-(4-(2-Pivalamidoethyl)piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide

Formula: C₁₉H₂₇N₅O₂S

Purity: 98%

Molecular weight: 389.52

Ref: IN-DG01123152

Sirt-IN-1

CAS: 1431411-60-7

Inhibitor of pan-sirtuins (IC50 = 15, 10, 33 µM for SIRT1, 2 and 3 respectively), by binding to the active catalytic site. Selectivity for sirtuins was demonstrated when tested for activity on a panel of kinases, nuclear receptors, ion channels, transporters and GPCRs.

Formula: C₁₉H₂₇N₅O₂S

Purity: Min. 95%

Molecular weight: 389.52 g/mol

Ref: 3D-BT166491

SIRT-IN-1

CAS: 1431411-60-7

SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).

Formula: C₁₉H₂₇N₅O₂S

Purity: 99.29%

Color and Shape: Solid

Molecular weight: 389.52

Ref: TM-T12918