
CAS 1431698-10-0
:Formula:C25H29Cl3N4O2
InChI:InChI=1S/C25H28Cl2N4O2.ClH/c1-14(32)18-12-28-22-9-8-21(16-10-19(26)25(33)20(27)11-16)30-24(22)23(18)29-17-6-4-15(5-7-17)13-31(2)3;/h8-12,15,17,33H,4-7,13H2,1-3H3,(H,28,29);1H
InChI key:XDGWHISAOWEFML-UHFFFAOYSA-N
SMILES:CC(=O)C1=CN=C2C=CC(=NC2=C1NC3CCC(CC3)CN(C)C)C4=CC(=C(C(=C4)Cl)O)Cl.Cl
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OTSSP167 hydrochloride
CAS:OTSSP167 hydrochlorideFormula:C25H29Cl3N4O2Purity:99%Molecular weight:523.881-(6-(3,5-Dichloro-4-hydroxyphenyl)-4-((trans-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethanone hydrochloride
CAS:Formula:C25H29Cl3N4O2Purity:99%Molecular weight:523.8824OTSSP167 hydrochloride
CAS:OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).Formula:C25H29Cl3N4O2Purity:99.41%Color and Shape:SolidMolecular weight:523.882OTSSP167 hydrochloride
CAS:OTSSP167 hydrochloride is a member of the family of small molecules that are used for cancer treatment. It binds to the kinase domain and inhibits the phosphorylation of proteins which are important in cell cycle progression, leading to cell death. OTSSP167 hydrochloride has been shown to inhibit the proliferation of cancer cells in culture and is also active against pluripotent stem cells. The binding affinity for this compound has been determined using various assays, including binding experiments and hydrophobic constant calculations.
Formula:C25H29Cl3N4O2Purity:Min. 95%Molecular weight:523.88 g/mol




