CAS 1432729-22-0

Formula: C21H22F3N5O2

InChI: InChI=1S/C21H22F3N5O2/c1-12-8-29(11-19(31-12)21(22,23)24)9-13-3-4-15-16(14-7-26-28(2)10-14)6-18(20(25)30)27-17(15)5-13/h3-7,10,12,19H,8-9,11H2,1-2H3,(H2,25,30)/t12-,19-/m1/s1

InChI key: KTYWQIWONODXST-CWTRNNRKSA-N

SMILES: C[C@@H]1CN(C[C@@H](O1)C(F)(F)F)CC2=CC3=C(C=C2)C(=CC(=N3)C(=O)N)C4=CN(N=C4)C

MK-8768

CAS: 1432729-22-0

MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by

Formula: C₂₁H₂₂F₃N₅O₂

Color and Shape: Solid

Molecular weight: 433.43

Ref: TM-T79302