CAS 14347-78-5

R-(-)-Sollketal

Description:

R-(-)-Sollketal, with the CAS number 14347-78-5, is a chiral compound primarily used in the field of organic chemistry and pharmaceuticals. It is characterized by its specific stereochemistry, which contributes to its biological activity and potential therapeutic applications. This compound is a derivative of ketone and alcohol, featuring a bicyclic structure that enhances its stability and reactivity. R-(-)-Sollketal is known for its role as a chiral auxiliary in asymmetric synthesis, facilitating the production of enantiomerically pure compounds. Its solubility properties typically allow it to dissolve in organic solvents, making it suitable for various chemical reactions. Additionally, the compound's unique configuration can influence its interaction with biological systems, which is of particular interest in drug development. Safety data sheets indicate that, like many organic compounds, it should be handled with care, considering potential hazards associated with its use. Overall, R-(-)-Sollketal is a valuable substance in synthetic organic chemistry, particularly in the context of creating complex molecules with specific stereochemical requirements.

Formula: C₆H₁₂O₃

InChI: InChI=1/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3

InChI key: InChIKey=RNVYQYLELCKWAN-RXMQYKEDSA-N

SMILES: C(O)[C@H]1OC(C)(C)OC1

Synonyms:

• ((4R)-2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
• ((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)methanol
• (-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
• (-)-2,3-O-Isopropylidene-Sn-Glycerol
• (-)-Solketal
• (-)-α,β-Isopropylideneglycerol
• (2R)-Glycerol 1,2-acetonide
• (4R)-2,2-Dimethyl-1,3-dioxolane-4-methanol
• (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol
• (R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-methanol
• (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol (-)-2,3-O-Isopropylidene-sn-glycerol
• (R)-(-)-Solketal
• (R)-1,2-Isopropylideneglycerol
• (R)-1,2-O-Isopropylideneglycerol
• (R)-2,3-Isopropylideneglycerol
• (R)-2,3-O-Isopropylideneglycerol
• (R)-Glycerol acetonide
• (R)-Isopropylideneglycerol
• 1,3-Dioxolane-4-methanol 2,2-dimethyl-, (4R)-
• 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, (R)-
• 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, <span class="text-smallcaps">D</span>-
• 2,2-Dimethyl-(4R)-1,3-dioxolane-4-methanol
• 2,3-Isopropylidene-<span class="text-smallcaps">L</span>-glycerol
• 2,3-Isopropylidene-sn-glycerol
• <span class="text-smallcaps">D</span>-2,2-Dimethyl-1,3-dioxolane-4-methanol
• 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, D-
• D-2,2-Dimethyl-1,3-dioxolane-4-methanol
• L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL
• (R)-2,2-dimethyl-1,3-dioxalone-4-methanol
• L-Glycerol-acetonide
• L-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL
• (R)-2,3-ISOPROPYLIDENE GLYCEROL
• 2,3-O-ISOPROPYLIDENE-L-GLYCEROL
• (R)-(-)-2,2-DIMETHYL-4-HYDROXYMETHYL-1,3-DIOXOLANE
• L-(-)-1,2-ISOPROPYLIDENEGLYCEROL

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

CAS: 14347-78-5

Formula: C₆H₁₂O₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 132.16

Ref: 3B-D1705

(R)-(-)-2,3-O-Isopropylideneglycerol, 96%

CAS: 14347-78-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₂O₃

Purity: 96%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 132.16

Ref: 02-B23037

(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol

CAS: 14347-78-5

Formula: C₆H₁₂O₃

Purity: 98%

Color and Shape: Liquid

Molecular weight: 132.1577

Ref: IN-DA003AYM

(R)-(-)-1,2-O-Isopropylideneglycerol

CAS: 14347-78-5

Formula: C₆H₁₂O₃

Molecular weight: 132.18

Ref: 7W-GC6030

(R)-(-)-1,2-O-Isopropylideneglycerol

CAS: 14347-78-5

(R)-(-)-1,2-O-Isopropylideneglycerol

Formula: C₆H₁₂O₃

Purity: 98%

Color and Shape: Pale yellow Liquid

Molecular weight: 132.15767

Ref: 54-OR51885

(R)-(-)-1,2-O-Isopropylideneglycerol

CAS: 14347-78-5

Isopropylideneglycerol is a chemical compound that has the formula (R)-(-)-1,2-O-isopropylideneglycerol. It is a colorless oil with a sweet taste and is soluble in water. Isopropylideneglycerol serves as an intermediate in the biosynthesis of glycerolipids, such as phosphoglycerides, glycerophosphoglycerides, and sphingomyelins. It also exhibits antioxidant activity and can protect cells from lipid peroxidation induced by reactive oxygen species. Isopropylideneglycerol has been shown to exhibit antitumour activity against ovarian cancer cells. This may be due to its ability to inhibit the activity of lipolytic enzymes in these cells.

Formula: C₆H₁₂O₃

Purity: Min. 97.0 Area-%

Color and Shape: Colorless Yellow Clear Liquid

Molecular weight: 132.16 g/mol

Ref: 3D-FI09513

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

CAS: 14347-78-5

Formula: C₆H₁₂O₃

Purity: 95%

Color and Shape: Clear

Molecular weight: 132.159

Ref: 10-F001472

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Controlled Product

CAS: 14347-78-5

Applications A MEK inhibitor with antitumor activity.
References Lee, W., et al.: Bioorg. Med. Chem. Lett., 15, 3573 (2005), Normanno, N., et al.: J. Cell. Physiology, 207, 420 (2006), Narlawar, R., et al.: J. Med. Chem., 49, 7588 (2006),

Formula: C₆H₁₂O₃

Color and Shape: Neat

Molecular weight: 132.16

Ref: TR-D472630