CAS 143900-43-0

(R)-1-Boc-3-hydroxypiperidine

Description:

(R)-1-Boc-3-hydroxypiperidine, with the CAS number 143900-43-0, is a chiral piperidine derivative characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group at the nitrogen atom and a hydroxyl group at the 3-position of the piperidine ring. This compound is typically used in organic synthesis, particularly in the preparation of pharmaceuticals and biologically active molecules, due to its ability to serve as a versatile building block. The Boc group provides stability and protection during chemical reactions, allowing for selective functionalization of the hydroxyl group. The stereochemistry of the (R) configuration is crucial for its biological activity, as it can influence the compound's interaction with biological targets. Additionally, (R)-1-Boc-3-hydroxypiperidine is soluble in organic solvents, making it suitable for various synthetic applications. Its properties, such as melting point, boiling point, and reactivity, can vary depending on the specific conditions and the presence of other functional groups in a reaction mixture.

Formula: C₁₀H₁₉NO₃

InChI: InChI=1/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h8,12H,4-7H2,1-3H3/t8-/m1/s1

SMILES: CC(C)(C)OC(=O)N1CCC[C@H](C1)O

Synonyms:

• 1-Piperidinecarboxylic Acid, 3-Hydroxy-, 1,1-Dimethylethyl Ester, (3R)-
• Tert-Butyl (3R)-3-Hydroxypiperidine-1-Carboxylate
• Ibrutinib Intermediate-1
• (R)-tert-butyl 3-hydroxypiperidine-1-carboxylate

(R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine

CAS: 143900-43-0

Formula: C₁₀H₁₉NO₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to lump

Molecular weight: 201.27

Ref: 3B-B4199

(R)-1-Boc-3-hydroxypiperidine, 97%

CAS: 143900-43-0

(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors. This Thermo Scientific Chemicals brand produc

Formula: C₁₀H₁₉NO₃

Purity: 97%

Color and Shape: Solid, White

Molecular weight: 201.27

Ref: 02-H52556

(R)-1-Boc-3-Hydroxypiperidine

CAS: 143900-43-0

Formula: C₁₀H₁₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 201.2628

Ref: IN-DA0032EL

(3R)-3-Hydroxypiperidine, N-BOC protected

CAS: 143900-43-0

(3R)-3-Hydroxypiperidine, N-BOC protected

Formula: C₁₀H₁₉NO₃

Purity: 98%

Color and Shape: white to off white solid

Molecular weight: 201.26g/mol

Ref: 54-OR4584

(R)-1-Boc-3-hydroxypiperidine

CAS: 143900-43-0

Formula: C₁₀H₁₉NO₃

Molecular weight: 201.27

Ref: ST-EA-CP-I20005

(R)-1-Boc-3-hydroxypiperidine

Controlled Product

CAS: 143900-43-0

Applications (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. (R)-1-Boc-3-hydroxypiperidine has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kikuchi, T., et. al.: J. Labelled Comptd. Rad., 44, 31 (2001); Isakovic, L., et. al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009)

Formula: C₁₀H₁₉NO₃

Color and Shape: Neat

Molecular weight: 201.26

Ref: TR-B656655

(R)-1-N-Boc-3-Hydroxypiperidine

CAS: 143900-43-0

Formula: C₁₀H₁₉NO₃

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 201.266

Ref: 10-F040534