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CAS 144060-53-7

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Febuxostat

Description:
Febuxostat is a xanthine oxidase inhibitor primarily used in the management of hyperuricemia associated with gout. It is characterized by its ability to reduce uric acid levels in the blood by inhibiting the enzyme responsible for uric acid production. The chemical formula of febuxostat reflects its complex structure, which includes a pyrimidine ring and various functional groups that contribute to its pharmacological activity. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Febuxostat is known for its efficacy in lowering uric acid levels compared to allopurinol, another common treatment for gout, and is often prescribed for patients who are intolerant to allopurinol or for whom it is ineffective. The substance is generally well-tolerated, though it may have side effects, including liver enzyme elevations and gastrointestinal disturbances. As with any medication, monitoring and consultation with a healthcare provider are essential to ensure safe and effective use.
Formula:C16H16N2O3S
InChI:InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
InChI key:InChIKey=BQSJTQLCZDPROO-UHFFFAOYSA-N
SMILES:C(O)(=O)C=1SC(=NC1C)C2=CC(C#N)=C(OCC(C)C)C=C2
Synonyms:
  • 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid
  • 2-[3-Cyano-4-(2-Methylpropoxy)Phenyl]-4-Methylthiazole-5-Carboxylic Acid
  • 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
  • 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid
  • 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid
  • 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-
  • Adenuric
  • Febugood
  • Feburic
  • Febutaz
  • See more synonyms
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