CAS 1445830-39-6

Formula: C24H24F2N6O3

InChI: InChI=1S/C24H24F2N6O3/c1-5-35-16-10-18(25)17(19(26)11-16)13-32-24(34-4)14(2)21(31-32)23-28-12-20(33-3)22(30-23)29-15-6-8-27-9-7-15/h6-12H,5,13H2,1-4H3,(H,27,28,29,30)

InChI key: LMRCQVHTZUUHFN-UHFFFAOYSA-N

SMILES: CCOC1=CC(=C(C(=C1)F)CN2C(=C(C(=N2)C3=NC=C(C(=N3)NC4=CC=NC=C4)OC)C)OC)F

BAY-524

CAS: 1445830-39-6

BAY-524

Formula: C₂₄H₂₄F₂N₆O₃

Purity: 99%

Molecular weight: 482.48

Ref: 54-BUP01532

BAY-524

CAS: 1445830-39-6

BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).

Formula: C₂₄H₂₄F₂N₆O₃

Purity: 98.68% - 99.57%

Color and Shape: White Solid

Molecular weight: 482.4826

Ref: TM-T14505

BAY-524

CAS: 1445830-39-6

Formula: C₂₄H₂₄F₂N₆O₃

Molecular weight: 482.4826

Ref: IN-DA01JPR7

BAY-524

CAS: 1445830-39-6

BAY-524 is a selective inhibitor of the protein methyltransferase PRMT5, derived from proprietary chemical synthesis methods. PRMT5 is an enzyme involved in the symmetrical dimethylation of arginine residues on substrate proteins, playing a crucial role in regulating gene expression and maintaining cellular homeostasis. BAY-524 targets PRMT5, thereby modulating methylation processes critical for cellular proliferation and survival. This compound exhibits high specificity and affinity for PRMT5, effectively inhibiting its activity and leading to altered gene expression profiles within affected cells.

Formula: C₂₄H₂₄F₂N₆O₃

Purity: Min. 95%

Molecular weight: 482.5 g/mol

Ref: 3D-VHC83039