CAS 1446090-79-4

Lifirafenib

CAS: 1446090-79-4

Lifirafenib

Formula: C₂₅H₁₇F₃N₄O₃

Purity: ≥95%

Molecular weight: 478.42

Ref: 54-BUP03697

Lifirafenib

CAS: 1446090-79-4

Formula: C₂₅H₁₇F₃N₄O₃

Molecular weight: 478.43

Ref: 4Z-L-240001

Lifirafenib

CAS: 1446090-79-4

5-(((1R,1aS,6bR)-1-(6-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one

Formula: C₂₅H₁₇F₃N₄O₃

Purity: 98%

Molecular weight: 478.42

Ref: IN-DG632486

Lifirafenib

CAS: 1446090-79-4

Lifirafenib is a potent and selective kinase inhibitor, which is synthetically derived. It operates by targeting and inhibiting specific pathways involving the RAF kinases within the MAPK/ERK signaling cascade. This interruption is critical in the control of cellular proliferation and survival, pathways often dysregulated in various cancers. Lifirafenib is particularly effective against BRAF-mutant cancers, including melanoma and certain types of thyroid and colorectal cancers.

Formula: C₂₅H₁₇F₃N₄O₃

Purity: Min. 95%

Molecular weight: 478.42 g/mol

Ref: 3D-WHC09079

Lifirafenib

CAS: 1446090-79-4

Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant

Formula: C₂₅H₁₇F₃N₄O₃

Purity: 97.99% - 98%

Color and Shape: Solid

Molecular weight: 478.42

Ref: TM-T22272

Lifirafenib

CAS: 1446090-79-4

Formula: C₂₅H₁₇F₃N₄O₃

Molecular weight: 478.43

Ref: 4Z-K-031174