CAS 14507-51-8

(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol

Description:

The chemical substance "(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol," with the CAS number 14507-51-8, is a synthetic steroid compound that belongs to the class of progestins. It is characterized by its complex steroidal structure, which includes a modified pregnane backbone with specific substitutions that influence its biological activity. The presence of the ethyl group at the 13-position and the methoxy group at the 3-position are notable features that can affect its pharmacological properties, including receptor binding affinity and metabolic stability. This compound is primarily studied for its potential applications in hormone replacement therapy and contraceptive formulations. Its unique structural modifications may enhance its selectivity and efficacy in interacting with progesterone receptors, making it a subject of interest in medicinal chemistry and pharmacology. As with many steroid derivatives, its solubility, stability, and biological activity can be influenced by the presence of functional groups and the overall stereochemistry of the molecule.

Formula: C₂₂H₃₀O₂

InChI: InChI=1S/C22H30O2/c1-4-21-12-10-18-17-9-7-16(24-3)14-15(17)6-8-19(18)20(21)11-13-22(21,23)5-2/h2,7,18-20,23H,4,6,8-14H2,1,3H3/t18-,19-,20+,21+,22+/m1/s1

InChI key: InChIKey=CQXCBGIFQZKDED-AANPDWTMSA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](CC1)(C4=C(CC3)CC(OC)=CC4)[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol
• (8R,9S,13S,14S,17R)-13-ethyl-17-ethynyl-3-methoxy-4,6,7,8,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
• 13-Ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol
• 18,19-Dinor-17α-pregna-2,5(10)-dien-20-yn-17-ol, 13-ethyl-3-methoxy-
• 18,19-Dinorpregna-2,5(10)-dien-20-yn-17-ol, 13-ethyl-3-methoxy-, (17α)-

Levonorgestrel EP Impurity T

CAS: 14507-51-8

Formula: C₂₂H₃₀O₂

Molecular weight: 326.48

Ref: ST-EA-CP-L19020

18,19-Dinorpregna-2,5(10)-dien-20-yn-17-ol, 13-ethyl-3-methoxy-, (17α)-

CAS: 14507-51-8

Formula: C₁₂H₁₅N

Color and Shape: Solid

Molecular weight: 173.2542

Ref: IN-DA001KJS

Levonorgestrel EP Impurity T

CAS: 14507-51-8

Formula: C₂₂H₃₀O₂

Color and Shape: White To Off-White Solid

Molecular weight: 326.48

Ref: 4Z-L-2225

(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol (levonorgestrel impurity T)

Controlled Product

CAS: 14507-51-8

(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-2,5(10)-dien-20-yn-17-ol (levonorgestrel impurity T) is an analog of levonorgestrel with potent anticancer properties. It has been shown to induce apoptosis in human cancer cell lines by inhibiting kinase and elastase activities. This compound has also been tested against a variety of tumor cell lines and has demonstrated significant anticancer activity. In Chinese hamster ovary cells, levonorgestrel impurity T was found to arrest the cell cycle at the G1 phase, leading to decreased protein synthesis and ultimately cell death. As an inhibitor of kinases and other enzymes involved in cellular signaling pathways, this compound may have potential as a therapeutic agent for the treatment of cancer.

Formula: C₂₂H₃₀O₂

Purity: Min. 95%

Molecular weight: 326.5 g/mol

Ref: 3D-PAA50751