CAS 145084-28-2

(R)-N-[2,3-DIHYDRO-1-[2-(2-METHYLPHENYL)-2-OXOETHYL]-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-N'-(3-METHYLPHENYL)-UREA

Formula: C₃₂H₂₈N₄O₃

InChI: InChI=1/C32H28N4O3/c1-21-11-10-15-24(19-21)33-32(39)35-30-31(38)36(20-28(37)25-16-7-6-12-22(25)2)27-18-9-8-17-26(27)29(34-30)23-13-4-3-5-14-23/h3-19,30H,20H2,1-2H3,(H2,33,35,39)/t30-/m0/s1

SMILES: Cc1cccc(c1)N=C(N[C@H]1C(=O)N(CC(=O)c2ccccc2C)c2ccccc2C(=N1)c1ccccc1)O

Synonyms:

• Ym 022
• 1-(3-methylphenyl)-3-{(3R)-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}urea

YM022

CAS: 145084-28-2

YM022

Formula: C₃₂H₂₈N₄O₃

Purity: 99.93%

Molecular weight: 516.59

Ref: 54-OR1115676

YM 022

Controlled Product

CAS: 145084-28-2

Formula: C₃₂H₂₈N₄O₃

Color and Shape: Neat

Molecular weight: 516.59

Ref: TR-Y100620

YM 022

Controlled Product

CAS: 145084-28-2

YM022 is an orally-administered small molecule that has been shown to bind to and inhibit the activity of MMP-9, a protease that plays a key role in tumor growth. YM022 also inhibits the activity of other proteases such as gastrin, epidermal growth factor receptor (EGFR), and collagenase. It has been shown to have anti-tumor effects by inhibiting tumor growth, increasing the time of tumor cell death, and reducing the size of tumors. This drug has also been shown to inhibit the production of peptide hormones such as gastrin and histidine. YM022 is not active against cells that do not express MMP-9 or EGFR.

Formula: C₃₂H₂₈N₄O₃

Purity: Min. 95%

Molecular weight: 516.59 g/mol

Ref: 3D-VFA08428

YM022

CAS: 145084-28-2

YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.

Formula: C₃₂H₂₈N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 516.59

Ref: TM-T17274

Urea, N-[(3R)-2,3-dihydro-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)-

CAS: 145084-28-2

Formula: C₃₂H₂₈N₄O₃

Purity: 99.93%

Molecular weight: 516.5897

Ref: IN-DA001KJD