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CAS 145108-58-3

:

dexmedetomidine HCL

Description:
Dexmedetomidine hydrochloride (CAS 145108-58-3) is a selective alpha-2 adrenergic agonist primarily used for its sedative and analgesic properties in clinical settings, particularly in intensive care and during surgical procedures. It is characterized by its ability to induce sedation without causing significant respiratory depression, making it a preferred choice for patients requiring sedation while maintaining airway reflexes. The compound is typically administered intravenously and has a rapid onset of action, with effects that can be reversed by the administration of specific antagonists. Dexmedetomidine exhibits a high affinity for alpha-2 adrenergic receptors, leading to decreased norepinephrine release and resulting in sedation, analgesia, and anxiolysis. Its pharmacokinetic profile includes a relatively short half-life, which allows for quick adjustments in sedation levels. Additionally, it is important to note that dexmedetomidine can have cardiovascular effects, including bradycardia and hypotension, necessitating careful monitoring during administration. Overall, dexmedetomidine hydrochloride is valued for its unique sedative properties and safety profile in various medical applications.
Formula:C13H17ClN2
InChI:InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
InChI key:InChIKey=VPNGEIHDPSLNMU-MERQFXBCSA-N
SMILES:[C@H](C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2.Cl
Synonyms:
  • (S)-4-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride
  • 1H-Imidazole, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride
  • 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride, (S)-
  • 1H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)
  • 4-((S)-Alpha,2,3-Trimethylbenzyl)Imidazole Monohydrochloride
  • 4-[(1R)-1-(2,3-Dimethylphenyl)Ethyl]-3H-Imidazole Hydrochloride
  • 5-[(1R)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1)
  • 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride
  • Cepedex
  • Dexdomitor
  • See more synonyms
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Found 17 products.
  • Dexmedetomidine Hydrochloride

    CAS:
    Formula:C13H16N2·HCl
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:236.74

    Ref: 3B-D5062

    20mg
    48.00€
    100mg
    161.00€
  • Ref: 61-FOR3355.00

    10mg
    144.00€
  • Dexmedetomidine Hydrochloride

    CAS:
    <p>Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi</p>
    Formula:C13H16N2·HCl
    Color and Shape:White Powder
    Molecular weight:200.13135
  • 1H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)

    CAS:
    Formula:C13H17ClN2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:236.7405

    Ref: IN-DA001KKV

    1g
    182.00€
    5g
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    25g
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    50g
    To inquire
    5mg
    63.00€
    10mg
    72.00€
    100mg
    96.00€
    250mg
    122.00€
  • Dexmedetomidine Hydrochloride

    CAS:
    <p>Dexmedetomidine Hydrochloride</p>
    Purity:99%
    Molecular weight:236.74g/mol

    Ref: 54-OR1025485

    1g
    308.00€
    5g
    1,314.00€
    100mg
    95.00€
    250mg
    113.00€
  • Dexmedetomidine hydrochloride

    CAS:
    <p>Dexmedetomidine hydrochloride</p>
    Purity:≥98%
    Molecular weight:236.74g/mol

    Ref: 54-BUP17795

    5mg
    57.00€
    10mg
    80.00€
    25mg
    136.00€
    50mg
    232.00€
    100mg
    328.00€
    200mg
    485.00€
  • Dexmedetomidine HCl

    CAS:
    Formula:C13H16N2·HCl
    Molecular weight:200.29 36.46

    Ref: 4Z-D-291001

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
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  • Dexmedetomidine hydrochloride, USP grade

    CAS:
    Formula:C13H16N2·HCl
    Purity:≤ 1.0% (of Levomedetomidine HCl)
    Color and Shape:White to off-white powder
    Molecular weight:236.74

    Ref: 7W-GX7871

    ne
    To inquire
  • Dexmedetomidine Hydrochloride

    Controlled Product
    CAS:
    Formula:C13H16N2·ClH
    Color and Shape:Neat
    Molecular weight:236.74

    Ref: 86-MM3355.00

    250mg
    1,809.00€
  • Dexmedetomidine hydrochloride

    CAS:
    <p>Dexmedetomidine hydrochloride (Precedex) is a potent, selective, orally active α2-adrenoceptor agonist.Cost-effective and quality-assured.</p>
    Formula:C13H16N2·HCl
    Purity:99.94% - 99.94%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:236.74
  • Dexmedetomidine hydrochloride

    CAS:
    Formula:C13H16N2·HCl
    Color and Shape:White to beige powder
    Molecular weight:236.74

    Ref: 7W-GW7920

    25mg
    55.00€
    100mg
    152.00€
  • Dexmedetomidine Hydrochloride

    Controlled Product
    CAS:
    Formula:C13H16N2·ClH
    Color and Shape:White To Off-White
    Molecular weight:236.74

    Ref: TR-D299008

    10mg
    121.00€
    50mg
    394.00€
    100mg
    616.00€
  • Dexmedetomidine hydrochloride

    Controlled Product
    CAS:
    <p>Dexmedetomidine hydrochloride is a drug that belongs to the class of drugs known as anesthetic agents. It is used to sedate patients before and during surgery or other procedures. Dexmedetomidine hydrochloride has shown clinical relevance in the treatment of diabetic neuropathy, with a reduction of pain and improvement in quality of life. It also has been shown to reduce postoperative ileus, which may be due to its ability to inhibit the release of inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Dexmedetomidine hydrochloride can be administered by intravenous or intramuscular injection. This drug does not have any effect on the cardiovascular system, although it does cause sedation and has been shown to increase heart rate. The drug is eliminated from the body through metabolism by cytochrome P450 enzymes in the liver, primarily CYP3A</p>
    Formula:C13H16N2•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:236.74 g/mol

    Ref: 3D-FD167004

    1g
    341.00€
    2g
    547.00€
    5g
    863.00€
    10g
    1,302.00€
    500mg
    233.00€
  • Dexmedetomidine hydrochloride - Bio-X ™

    Controlled Product
    CAS:
    <p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>
    Formula:C13H16N2•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:236.74 g/mol

    Ref: 3D-FD37014

    10mg
    135.00€
  • (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride

    CAS:
    Formula:C13H17ClN2
    Purity:98%
    Molecular weight:236.74

    Ref: 10-F462701

    1g
    239.00€
    5mg
    53.00€
    10mg
    75.00€
    100mg
    83.00€
    250mg
    96.00€
  • Dexmedetomidine hydrochloride

    CAS:
    Formula:C13H16N2HCl
    Molecular weight:200.29 : 36.46

    Ref: ST-EA-CP-D237000

    10mg
    To inquire
    25mg
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    50mg
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    100mg
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  • Dexmedetomidine hydrochloride

    CAS:
    Formula:C13H16N2HCl
    Molecular weight:200.29 : 36.46

    Ref: ST-EA-CP-M8021

    10mg
    To inquire
    25mg
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