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CAS 1453848-26-4

:

GDC-0994

Description:
GDC-0994, with the CAS number 1453848-26-4, is a small molecule inhibitor primarily targeting the mitogen-activated protein kinase (MAPK) pathway, specifically the extracellular signal-regulated kinase (ERK). It is designed to interfere with the signaling pathways that are often dysregulated in various cancers, making it a candidate for cancer therapy. The compound exhibits selective inhibition of ERK, which is crucial for cell proliferation and survival. GDC-0994 has been evaluated in preclinical studies and clinical trials for its efficacy in treating tumors with specific genetic mutations. Its pharmacological profile includes properties such as oral bioavailability and a favorable safety margin, although detailed toxicity and side effect profiles are typically assessed during clinical development. The compound's structure features a unique arrangement of functional groups that contribute to its binding affinity and specificity for the target enzyme. Overall, GDC-0994 represents a promising approach in targeted cancer therapy, particularly in the context of personalized medicine.
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