CAS 14599-46-3

5-carboxy-2'-deoxyuridine

Formula: C₁₀H₁₂N₂O₇

InChI: InChI=1S/C10H12N2O7/c13-3-6-5(14)1-7(19-6)12-2-4(9(16)17)8(15)11-10(12)18/h2,5-7,13-14H,1,3H2,(H,16,17)(H,11,15,18)/t5-,6+,7+/m0/s1

InChI key: InChIKey=GAGYTXTVUMXAOC-RRKCRQDMSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(O)=O)C(=O)N1

Synonyms:

• 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
• 2'-Deoxy-5-carboxyuridine
• 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
• 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
• Uridine, 5-Carboxy-2'-Deoxy-
• 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
• 5-Pyrimidinecarboxylic acid, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
• 5-Carboxy-2'-deoxyuridine
• 5-Carboxy-2′-deoxyuridine

TRIFLURIDINE IMPURITY A CRS

CAS: 14599-46-3

TRIFLURIDINE IMPURITY A CRS

Ref: 41-Y0002207

Trifluridine Related Compound A

CAS: 14599-46-3

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₀H₁₂N₂O₇

Color and Shape: White Off-White Powder

Molecular weight: 272.06445

Ref: 45-1686310

5-Carboxy-2′-deoxyuridine

CAS: 14599-46-3

5-Carboxy-2′-deoxyuridine

Purity: ≥95%

Molecular weight: 272.21g/mol

Ref: 54-OR1004995

Trifluridine Related Compound A

CAS: 14599-46-3

Formula: C₁₀H₁₂N₂O₇

Color and Shape: Pale Yellow Solid

Molecular weight: 272.21

Ref: 4Z-T-182006

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid

CAS: 14599-46-3

Formula: C₁₀H₁₂N₂O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 272.2115

Ref: IN-DA001DLJ

5-Carboxy-2'-deoxyuridine

CAS: 14599-46-3

5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END>

Formula: C₁₀H₁₂N₂O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 272.21 g/mol

Ref: 3D-NC58344

5-Carboxy-2'-deoxyuridine

Controlled Product

CAS: 14599-46-3

Applications 5-Carboxy-2'-deoxyuridine, is a derivative of Trifluridine, an anti-herpesvirus antiviral drug, used primarily on the eye.
References Kuster, P., et al.: CLAO J. 24(2), 122 (1998); O’Brien, W., Invest. Opthalmol. Vis. Sci., 32 (9), 2455 (1991);

Formula: C₁₀H₁₂N₂O₇

Color and Shape: Neat

Molecular weight: 272.21

Ref: TR-C177965

Trifluridine EP Impurity A

CAS: 14599-46-3

Formula: C₁₀H₁₂N₂O₇

Molecular weight: 272.21

Ref: ST-EA-CP-T185001