CAS 146-22-5
:2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl-
Description:
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl- (CAS 146-22-5) is a chemical compound belonging to the benzodiazepine class, which is characterized by a fused benzene and diazepine ring structure. This compound typically exhibits a range of pharmacological properties, including anxiolytic, sedative, and muscle relaxant effects, although its specific activity can vary based on structural modifications. The presence of a nitro group at the 7-position and a phenyl group at the 5-position contributes to its unique chemical reactivity and potential biological activity. In terms of physical properties, benzodiazepines often display moderate solubility in organic solvents and limited solubility in water, which can influence their bioavailability and pharmacokinetics. The compound's molecular structure allows for interactions with the central nervous system, primarily through modulation of GABA receptors, making it of interest in medicinal chemistry and pharmacology. Safety and handling precautions are essential due to potential toxicity and side effects associated with benzodiazepine derivatives.
Formula:C15H11N3O3
InChI:InChI=1/C18H17ClN2O/c1-11(2)16-18(22)20-15-9-8-13(19)10-14(15)17(21-16)12-6-4-3-5-7-12/h3-11,16H,1-2H3,(H,20,22)
InChI key:InChIKey=KJONHKAYOJNZEC-UHFFFAOYSA-N
SMILES:N(=O)(=O)C=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Synonyms:- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepine-2-one
- 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
- 7-Nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
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- nitrazepam--dea schedule iv item
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl-
- 1,3-dihydro-7-nitro-5-phenyl-1,4-benzodiazepin-2-one
- 7-chloro-5-phenyl-3-(propan-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Apodorm
- 1H-1,4-Benzodiazepin-2(3H)-one, 7-chloro-3-isopropyl-5-phenyl-
- Cerson
- Eunoktin
- 7-Nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-dihydro-7-nitro-5-phenyl-2h-4-benzodiazepin-2-one
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Found 13 products.
Nitrazepam
CAS:Controlled ProductNitrazepam is a benzodiazepine with hypnotic and sedative properties. It binds to the GABA-A receptor in the brain, leading to an increase in the frequency of chloride ion channel opening. Nitrazepam has synergistic effects with other drugs such as antidepressants, antipsychotics, and antihistamines. It is used for the treatment of insomnia and anxiety disorders. Nitrazepam has been shown to have a rate constant of 0.068 L/mg at 25°C in human serum. This drug can be analyzed by gas chromatography following derivatization with methanol or ethyl acetate. Nitrazepam is one of many compounds found in wastewater that may cause long-term damage to the environment during wastewater treatment. The presence of nitrazepam in biological samples can be determined by a control analysis using a method that employs high performance liquid chromatography (HPLC). Nitrazepam can also be detected by polymerase chain reactionFormula:C15H11N3O3Purity:Min. 95%Color and Shape:SolidMolecular weight:281.27 g/molNitrazepam
CAS:Controlled ProductNitrazepam is a peptide that is used as a research tool for the study of ion channels and protein interactions. It has an affinity for GABA receptors and can be used to study the effects of receptor activation. Nitrazepam also binds to antibody-producing cells, which leads to increased production of antibodies by these cells. This drug is an inhibitor that blocks the binding of ligands to their receptors, thereby preventing or reversing the effects of ligand binding on cell function. Nitrazepam is a high-purity reagent with CAS No. 146-22-5, which can be used in life science research and cell biology.
Formula:C15H11N3O3Molecular weight:281.27 g/molNITRAZEPAM CRS - * PSY
CAS:Controlled ProductNITRAZEPAM CRS - * PSYFormula:C15H11N3O3Color and Shape:Added ModifiedMolecular weight:281.2661Nitrazepam
CAS:Controlled ProductNitrazepamFormula:C15H11N3O3Purity:100.0%Color and Shape:White To Off-WhiteMolecular weight:281.08004Nitrazepam (1.0 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C15H11N3O3Color and Shape:ColourlessMolecular weight:281.27Nitrazepam
CAS:Controlled ProductApplications Anticonvulsant; hypnotic.Controlled substance (depressant).
References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).Formula:C15H11N3O3Color and Shape:White To Off-WhiteMolecular weight:281.27Nitrazepam (100μg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C15H11N3O3Color and Shape:ColourlessMolecular weight:281.27
