CAS 146-68-9
:2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate
Description:
2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate, with the CAS number 146-68-9, is a chemical compound that belongs to the class of tetrazolium salts. It is characterized by its complex structure, which includes a tetrazolium ring and various aromatic substituents, specifically a 4-iodophenyl group and a 4-nitrophenyl group. This compound is typically encountered as a hydrate, indicating the presence of water molecules in its crystalline form. It is known for its application in biochemical assays, particularly in cell viability and proliferation studies, where it serves as a colorimetric indicator. The presence of the nitro and iodo substituents contributes to its unique electronic properties, influencing its reactivity and solubility. Additionally, the compound may exhibit specific spectral characteristics, making it useful in analytical chemistry. Safety precautions should be taken when handling this substance, as it may pose health risks due to its chemical nature.
Formula:C19H13ClIN5O2
InChI:InChI=1/C19H14IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H,(H,21,22);1H
InChI key:InChIKey=JORABGDXCIBAFL-UHFFFAOYSA-M
SMILES:N(=O)(=O)C1=CC=C([N+]=2N(N=C(N2)C3=CC=CC=C3)C4=CC=C(I)C=C4)C=C1.[Cl-]
Synonyms:- 1-iodo-1-nitro-1H-tetrazol-1-ium chloride
- 2-(4-Iodophenyl)-3-(4-Nitrophenyl)-5-Phenyltetrazolium Chloride
- 2-(4-Iodophenyl)-3-(4-Nitrophrnyl)-5-Phenyl-2H-Tetrazoliu Chloride
- 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride
- 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2,3-dihydro-1H-tetrazole hydrochloride (1:1)
- 2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride
- 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride
- 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride (1:1)
- 2H-Tetrazolium, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyl-, chloride
- 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium
- 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chloride
- 3-(P-Iodophenyl)-2-(P-Nitrophenyl)-5-Phenyl Tetrazolium Chloride
- 3-(p-Nitrophenyl)-2-(p-iodophenyl)-5-phenyltetrazolium chloride
- 4-Iodonitrotetrazolium Violet
- INT
- Int Chloride
- Iodonitro tetrazolium
- Iodonitrotetrazolium
- Iodonitrotetrazolium Chloride
- Iodonitrotetrazolium purple
- Iodonitrotetrazolium violet
- NSC 27620
- [2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyl-2H-tetrazolium chloride]
- p-Iodonitrotetrazolium violet
- INT, Iodonitrotetrazolium violet
- INT~2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate
- 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2h-tetrazoliuchloride
- IntA.R.
- 2(4-IODOPHENYL)-3(4-NITROPHENYL)-5-PHENYL-2H-Tetrazolium Chloride (INT)extrapure AR
- See more synonyms
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2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride
CAS:Formula:C19H13ClIN5O2Purity:>98.0%(HPLC)(T)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:505.702-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride [for Biochemical Research]
CAS:Formula:C19H13ClIN5O2Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:505.70Iodonitrotetrazolium violet, 95%
CAS:Used for dehydrogenase determination This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a partFormula:C19H13ClIN5O2Purity:95%Color and Shape:Powder, Cream to yellowMolecular weight:505.70Iodonitrotetrazolium chloride
CAS:Formula:C19H13ClIN5O2Purity:95%Color and Shape:SolidMolecular weight:505.6963Iodonitrotetrazolium chloride
CAS:Iodonitrotetrazolium chlorideFormula:C19H13IN5O2·ClPurity:By hplc: 99.6% by area (Typical Value in Batch COA)Color and Shape:Pale yellow Solid-PowderMolecular weight:505.696292-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride
CAS:Formula:C19H13ClIN5O2Purity:≥ 98.0%Color and Shape:Light-yellow to yellow powderMolecular weight:505.70INT
CAS:Iodonitrotetrazolium chloride (INT), serves as the electron acceptor in a range of dehydrogenase colorimetric analyses.Formula:C19H13ClIN5O2Purity:98.46% - 99.43%Color and Shape:Slightly Yellow PowderMolecular weight:505.696INT
CAS:2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chlorideFormula:C19H13ClIN5O2Purity:98%Molecular weight:505.72(4-Iodophenyl)-3 (4-Nitrophenyl)-5-Phenyl-2H-Tetrazolium Chloride (INT) extrapure AR, 98%
CAS:Formula:C19H13N5O2lCIPurity:min. 98%Color and Shape:White to Dark Yellow to Dark Orange, Crystalline powderMolecular weight:505.70Iodonitrotetrazolium Chloride (Technical Grade)
CAS:Formula:C19H13IN5O2•(Cl)Color and Shape:NeatMolecular weight:505.7Iodonitrotetrazolium chloride
CAS:The monotetrazolium salt Iodonitrotetrazolium chloride (INT), first described by Atkinson et al. (1950), is an iodinated derivative of TTC (2,3,5-Triphenyltetrazolium chloride) with an absorption λmax of 248 nm. The color produced by reduction of this iodonitro compound is a red to purple or brownish formazan with an absorption maximum at 485 to 492 nm (depending on the solvent). INT is often used to visualize dehydrogenase activity histochemically as well as in Western blot staining and as a staining agent for agar colony formation assays. NAD or NADP-dependent dehydrogenases activity assays: NAD+- or NADP+-dependent dehydrogenase transfers electrons from a substrate (the electron donor, e.g. succinate) to NAD+ or NADP+, forming NADH and NADPH, respectively. Then, the final transfer of hydrogen to the tetrazolium salt is catalyzed by NADH or NADPH dehydrogenases (e.g. succinate dehydrogenase), leading to the reduction of INT and formation of the water-insoluble INT-formazan. 1 mol of formazan is produced for each mole of succinate utilized in the presence of INT. It is important to mention for applications in histology, that INT-formazan precipitates at the site of this latter dehydrogenase but not at the site of the original NAD+- or NADP+-dependent dehydrogenase activity.Formula:C19H13ClIN5O2Molecular weight:505.7 g/mol
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