CAS 146-77-0

2-Chloroadenosine

Description:

2-Chloroadenosine is a modified nucleoside that consists of an adenine base linked to a ribose sugar, with a chlorine atom substituted at the 2-position of the ribose. Its molecular formula is C10H12ClN5O4, and it has a molecular weight that reflects its composition. This compound is known for its role in biochemical research, particularly in studies related to purinergic signaling and cellular processes. 2-Chloroadenosine can act as an agonist for adenosine receptors, influencing various physiological responses such as vasodilation and neurotransmission. It is often utilized in pharmacological studies to explore the effects of adenosine and its analogs on cellular functions. The presence of the chlorine atom alters the compound's reactivity and biological activity compared to adenosine. Additionally, 2-Chloroadenosine is soluble in water and exhibits stability under physiological conditions, making it a valuable tool in experimental settings. Its unique properties and interactions with biological systems make it significant in both research and potential therapeutic applications.

Formula: C₁₀H₁₂ClN₅O₄

InChI: InChI=1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

InChI key: InChIKey=BIXYYZIIJIXVFW-UUOKFMHZSA-N

SMILES: NC1=C2C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)=NC(Cl)=N1

Synonyms:

• 2-Chloradenosinhemihydrat
• 2-Chloro-<span class="text-smallcaps">D</span>-adenosine
• 2-Chloro-D-adenosine
• 2-Chloroadenosine
• 2-Chloroadenosine, hemihydrate
• 2-Chloroadenosinehemihydrate
• 2-Cloroadenosina, Hemihidrato
• Antibiotic AT 265B
• Cado
• Nsc 36896
• 6-amino-2-chloropurine riboside
• Adenosine, 2-chloro-

2-Chloroadenosine

CAS: 146-77-0

Formula: C₁₀H₁₂ClN₅O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 301.69

Ref: 3B-C2192

2-Chloroadenosine

CAS: 146-77-0

2-Chloroadenosine is used as a selective A1-adenosine receptor agonist, and also Induces apoptosis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar

Formula: C₁₀H₁₂ClN₅O₄

Color and Shape: Powder or crystalline powder, White to pale cream

Molecular weight: 301.69

Ref: 02-J63810

Adenosine, 2-chloro-

CAS: 146-77-0

Formula: C₁₀H₁₂ClN₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 301.6864

Ref: IN-DA001DM6

Regadenoson Impurity 5

CAS: 146-77-0

Formula: C₁₀H₁₂ClN₅O₄

Molecular weight: 301.69

Ref: 4Z-R-095006

6-Amino-2-Chloropurine Riboside

CAS: 146-77-0

6-Amino-2-Chloropurine Riboside

Purity: 98%

Molecular weight: 301.69g/mol

Ref: 54-OR1011978

2-Chloroadenosine

CAS: 146-77-0

2-Chloroadenosine

Purity: ≥98%

Molecular weight: 301.69g/mol

Ref: 54-BUP13603

2-Chloroadenosine

CAS: 146-77-0

Formula: C₁₀H₁₂ClN₅O₄

Purity: ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 301.69

Ref: 7W-GE9219

2-Chloroadenosine

CAS: 146-77-0

Color and Shape: Neat

Ref: 86-MM3772.03

2-Chloroadenosine

CAS: 146-77-0

2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively

Formula: C₁₀H₁₂ClN₅O₄

Purity: 99.23%

Color and Shape: White Powder

Molecular weight: 301.69

Ref: TM-T7736

2-Chloro Adenosine

CAS: 146-77-0

Applications A selective A1-adenosine receptor agonist. Induces apoptosis.
References Evans, et al.: Neurosci. Lett., 83, 287 (1987), Szondy, Z.: Biochem. J., 304, 877 (1994)

Formula: C₁₀H₁₂ClN₅O₄

Color and Shape: Off-White

Molecular weight: 301.69

Ref: TR-C364000

2-Chloroadenosine

CAS: 146-77-0

M04084 - 2-Chloroadenosine

Formula: C₁₀H₁₂ClN₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 301.69

Ref: 10-M04084

2-Chloroadenosine

CAS: 146-77-0

Formula: C₁₀H₁₂ClN₅O₄

Molecular weight: 301.69

Ref: ST-EA-CP-R55001

2-Chloroadenosine

CAS: 146-77-0

2-Chloroinosine is an adenosine receptor agonist; metabolically stable analog of adenosine

Formula: C₁₀H₁₂ClN₅O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 301.69 g/mol

Ref: 3D-NC06293