CAS 146062-49-9: Mitoglitazone
Description:Mitoglitazone is a synthetic compound belonging to the thiazolidinedione class of drugs, primarily used in the management of type 2 diabetes mellitus. It acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in glucose and lipid metabolism. The chemical formula of Mitoglitazone reflects its complex structure, which includes a thiazolidinedione moiety, contributing to its pharmacological activity. This compound is characterized by its ability to enhance insulin sensitivity, thereby improving glycemic control in diabetic patients. Mitoglitazone also exhibits anti-inflammatory and anti-atherogenic properties, making it of interest in cardiovascular research. However, like other thiazolidinediones, it may be associated with side effects such as weight gain and fluid retention. Its safety profile and efficacy have been subjects of clinical studies, and it is essential to consider these factors when evaluating its therapeutic use. As with any medication, it is crucial to consult healthcare professionals for personalized medical advice.
Formula:C19H18N2O4S
InChI:InChI=1S/C19H18N2O4S/c1-2-12-5-8-15(20-10-12)16(22)11-25-14-6-3-13(4-7-14)9-17-18(23)21-19(24)26-17/h3-8,10,17H,2,9,11H2,1H3,(H,21,23,24)
InChI key:InChIKey=IRNJSRAGRIZIHD-UHFFFAOYSA-N
SMILES:O=C1SC(C(=O)N1)CC2=CC=C(OCC(=O)C3=NC=C(C=C3)CC)C=C2
- Synonyms:
- 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione
- 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-
- MSDC 0160
- Mitoglitazone
- CAY 10415