CAS 146062-49-9

Mitoglitazone

Description:

Mitoglitazone is a synthetic compound belonging to the thiazolidinedione class of drugs, primarily used in the management of type 2 diabetes mellitus. It acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in glucose and lipid metabolism. The chemical formula of Mitoglitazone reflects its complex structure, which includes a thiazolidinedione moiety, contributing to its pharmacological activity. This compound is characterized by its ability to enhance insulin sensitivity, thereby improving glycemic control in diabetic patients. Mitoglitazone also exhibits anti-inflammatory and anti-atherogenic properties, making it of interest in cardiovascular research. However, like other thiazolidinediones, it may be associated with side effects such as weight gain and fluid retention. Its safety profile and efficacy have been subjects of clinical studies, and it is essential to consider these factors when evaluating its therapeutic use. As with any medication, it is crucial to consult healthcare professionals for personalized medical advice.

Formula: C₁₉H₁₈N₂O₄S

InChI: InChI=1S/C19H18N2O4S/c1-2-12-5-8-15(20-10-12)16(22)11-25-14-6-3-13(4-7-14)9-17-18(23)21-19(24)26-17/h3-8,10,17H,2,9,11H2,1H3,(H,21,23,24)

InChI key: InChIKey=IRNJSRAGRIZIHD-UHFFFAOYSA-N

SMILES: C(C1SC(=O)NC1=O)C2=CC=C(OCC(=O)C3=CC=C(CC)C=N3)C=C2

Synonyms:

• 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione
• 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-
• MSDC 0160
• Mitoglitazone
• CAY 10415

2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-

CAS: 146062-49-9

Formula: C₁₉H₁₈N₂O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 370.4222

Ref: IN-DA001DMZ

5-(4-(2-(5-Ethylpyridin-2-yl)-2-Oxoethoxy)Benzyl)Thiazolidine-2,4-Dione

CAS: 146062-49-9

5-(4-(2-(5-Ethylpyridin-2-yl)-2-Oxoethoxy)Benzyl)Thiazolidine-2,4-Dione

Purity: 97%

Molecular weight: 370.42g/mol

Ref: 54-OR1023810

MSDC 0160

CAS: 146062-49-9

MSDC 0160

Purity: ≥98%

Molecular weight: 370.42g/mol

Ref: 54-BUP03409

MSDC 0160

CAS: 146062-49-9

MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.

Formula: C₁₉H₁₈N₂O₄S

Purity: 98.11% - 99.53%

Color and Shape: Solid

Molecular weight: 370.42

Ref: TM-T2607

5-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione

CAS: 146062-49-9

Purity: 97.0%

Molecular weight: 370.4200134277344

Ref: 10-F540283

CAY10415

Controlled Product

CAS: 146062-49-9

Applications CAY10415 is used to study blood glucose levels and rates of insulin-stimulated lipogenesis.
References Dumbare, M., et al.: Int. Res J. Pharmacy, 8, 12 (2017)

Formula: C₁₉H₁₈N₂O₄S

Color and Shape: Neat

Molecular weight: 370.422

Ref: TR-C227028