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IGF-1R

IGF-1R

IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.

Found 119 products for "IGF-1R".

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  • Ganitumab
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    Ganitumab

    CAS:
    Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.
    Purity:100% (SEC-HPLC) - > 95%
    Color and Shape:Transparent Liquid
    Molecular weight:145.70 kDa (Predicted)

    Ref: TM-T76810

  • ALK inhibitor 1
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    ALK inhibitor 1

    CAS:
    ALK inhibitor 1 is a selective ALK kinase inhibitor.
    Formula:C23H28BrN7O3S
    Purity:98.27%
    Color and Shape:White Solid
    Molecular weight:562.483

    Ref: TM-T10285

  • GIP (3-42), human
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    GIP (3-42), human

    CAS:
    Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.
    Formula:C214H324N58O63S
    Purity:95.73%
    Color and Shape:Solid
    Molecular weight:4749.35

    Ref: TM-T37589

  • Robatumumab
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    Robatumumab

    CAS:
    Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.
    Purity:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:145.56 kDa (Predicted)

    Ref: TM-T76759

  • NBI-31772
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    NBI-31772

    CAS:
    NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).
    Formula:C17H11NO7
    Purity:99.37% - 99.79%
    Color and Shape:Yellow Solid
    Molecular weight:341.27

    Ref: TM-T8906

  • MSDC-0602K
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    MSDC-0602K

    CAS:
    MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.
    Formula:C19H16KNO5S
    Purity:99.42%
    Color and Shape:White Solid
    Molecular weight:409.5

    Ref: TM-T38715

  • Teprotumumab
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    Teprotumumab

    CAS:
    Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.
    Purity:/ - 95.2% (SDS-PAGE); 99.6% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:145.62 kDa (Predicted)

    Ref: TM-T76727

  • GIP (human) acetate
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    GIP (human) acetate

    GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.
    Purity:98.65%
    Color and Shape:Solid

    Ref: TM-TP2018L

  • AZ7550 hydrochloride
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    AZ7550 hydrochloride

    CAS:
    AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
    Formula:C27H32ClN7O2
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:522.042

    Ref: TM-T13564L

  • HNMPA
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    HNMPA

    CAS:
    HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
    Formula:C11H11O4P
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:238.18

    Ref: TM-T21761

  • Acetyl Gastric Inhibitory Peptide (human)
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    Acetyl Gastric Inhibitory Peptide (human)

    CAS:
    Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.
    Formula:C228H340N60O67S
    Color and Shape:Solid
    Molecular weight:5025.6

    Ref: TM-T76310

  • Gastric Inhibitory Peptide (1-42) (porcine) TFA
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    Gastric Inhibitory Peptide (1-42) (porcine) TFA

    Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.
    Formula:C225H342N60O66S·XCF3COOH
    Color and Shape:White Solid
    Molecular weight:4975.55

    Ref: TM-T83694

  • IGF-I (24-41)
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    IGF-I (24-41)

    CAS:
    IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.
    Formula:C88H133N27O28
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2017.16

    Ref: TM-TP1124

  • WAY-270250
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    WAY-270250

    CAS:
    WAY-270250 is an IGF-1R/SRC inhibitor.
    Formula:C18H16N2O2
    Purity:99.97%
    Color and Shape:Green Solid
    Molecular weight:292.33

    Ref: TM-T77624

  • GIP, human
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    GIP, human

    CAS:
    Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.
    Formula:C226H338N60O66S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4983.6

    Ref: TM-TP2018

  • CymitQuimica logo
    Targetmol
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    Insulin peglispro

    CAS:
    Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.
    Formula:C370H566N104O110S4
    Color and Shape:Solid
    Molecular weight:8359.32

    Ref: TM-T76540

  • (Pro3) GIP, human
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    (Pro3) GIP, human

    CAS:
    (Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.
    Formula:C226H338N60O64S
    Color and Shape:Solid
    Molecular weight:4951.53

    Ref: TM-T76313

  • IGF-1R inhibitor-2
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    IGF-1R inhibitor-2

    CAS:
    IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.
    Formula:C24H24FN7O2
    Color and Shape:Solid
    Molecular weight:461.501

    Ref: TM-T38502

  • cis-NVP-ADW742
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    cis-NVP-ADW742

    CAS:
    NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
    Formula:C28H31N5O
    Color and Shape:Solid
    Molecular weight:453.59

    Ref: TM-T2107

  • [D-Ala2]-GIP (human)
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    [D-Ala2]-GIP (human)

    CAS:
    [D-Ala2]-GIP (human), GIP agonist (EC₅₀=630 pM), improves glucose/cognition, anti-neurotoxicity, for diabetes and Parkinson's.
    Formula:C226H338N60O66S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4983.58

    Ref: TM-TP2019