CAS 14678-02-5

5-Amino-3-methylisoxazole

Description:

5-Amino-3-methylisoxazole is an organic compound characterized by its isoxazole ring, which is a five-membered heterocyclic structure containing both nitrogen and oxygen atoms. This compound features an amino group (-NH2) and a methyl group (-CH3) attached to the isoxazole ring, contributing to its unique chemical properties. It is typically a white to off-white crystalline solid and is soluble in polar solvents, such as water and alcohols, due to the presence of the amino group, which can engage in hydrogen bonding. The compound is of interest in various fields, including medicinal chemistry, where it may exhibit biological activity, potentially serving as a building block for pharmaceuticals or agrochemicals. Its reactivity can be influenced by the functional groups present, allowing for various chemical transformations. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₄H₆N₂O

InChI: InChI=1S/C4H6N2O/c1-3-2-4(5)7-6-3/h2H,5H2,1H3

InChI key: InChIKey=FNXYWHTZDAVRTB-UHFFFAOYSA-N

SMILES: CC=1C=C(N)ON1

Synonyms:

• 3-Methyl-1,2-Oxazol-5-Amine
• 3-Methyl-1,2-oxazol-5-ylamine
• 3-Methyl-5-Aminoisoxazole
• 3-Methyl-5-Isoxazolamin
• 3-Methyl-5-isoxazolamine
• 3-Methyl-5-isoxazolylamine
• 5-Amino-3-Methylisoxazole
• 5-Amino-3-methyl-1,2-oxazole
• 5-Isoxazolamine, 3-methyl-
• Isoxazole, 5-amino-3-methyl-
• NSC 93421

5-Amino-3-methylisoxazole

CAS: 14678-02-5

Formula: C₄H₆N₂O

Purity: >97.0%(T)

Color and Shape: White - Yellow Solid Form

Molecular weight: 98.11

Ref: 3B-A2867

5-Amino-3-methylisoxazole, 98%

CAS: 14678-02-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₆N₂O

Purity: 98%

Color and Shape: White to cream or pale yellow to yellow to orange, Crystals or powder or crystalline powder

Molecular weight: 98.11

Ref: 02-A12446

5-Isoxazolamine, 3-methyl-

CAS: 14678-02-5

Formula: C₄H₆N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 98.1032

Ref: IN-DA001EBF

5-Amino-3-methylisoxazole

CAS: 14678-02-5

5-Amino-3-methylisoxazole

Formula: C₄H₆N₂O

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 98.10323

Ref: 54-OR7410

5-Amino-3-methylisoxazole

CAS: 14678-02-5

Formula: C₄H₆N₂O

Molecular weight: 98.11

Ref: 7W-GK8263

5-Amino-3-methylisoxazole

CAS: 14678-02-5

5-Amino-3-methylisoxazole

Formula: C₄H₆N₂O

Purity: 97%

Molecular weight: 98.1

Ref: IN-DG2304

5-Amino-3-methylisoxazole

CAS: 14678-02-5

5-Amino-3-methylisoxazole is a tetronic acid that can be switched between two forms, the cis and trans form. It is a structural analogue of salicylaldehyde and has a similar functional theory. 5-Amino-3-methylisoxazole is an intermediate in the synthesis of quinoline derivatives, sulfa drugs and other chemicals. It can also be used as an antibacterial agent because it has been shown to have activity against E. coli and Staphylococcus aureus. The cis form of 5-amino-3-methylisoxazole is formed when it reacts with chloride ions or sodium salts under ultrasonication. This activated form has been shown to have antimicrobial activity against gram negative bacteria such as E. coli and Salmonella typhi, although not for gram positive bacteria such as S. aureus or Proteus vulgaris. The trans form of the molecule contains no

Formula: C₄H₆N₂O

Purity: Min. 95%

Molecular weight: 98.1 g/mol

Ref: 3D-FA11918

5-Amino-3-methylisoxazole

CAS: 14678-02-5

Formula: C₄H₆N₂O

Purity: 96%

Color and Shape: Solid

Molecular weight: 98.105

Ref: 10-F018187

5-Amino-3-methylisoxazole

Controlled Product

CAS: 14678-02-5

Applications 5-Amino-3-methylisoxazole is a widely used reactant. 5-Amino-3-methylisoxazole has been used as a reactant for the preparation of heterocycle fused pyridinecarboxylic acids.
References Volochnyuk, D.M., et. al.: J. Comb. Chem., 12, 510 (2010)

Formula: C₄H₆N₂O

Color and Shape: Neat

Molecular weight: 98.1

Ref: TR-A616895