CAS 1469284-79-4

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate: oral, potent, selective DGAT2 inhibitor (IC50=14 nM), noncompetitive, slowly reversible.

Formula: C₂₃H₃₀ClN₇O₄S

Purity: 99.77% - 99.9%

Color and Shape: Solid

Molecular weight: 536.05

Ref: TM-T12425

[(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanonemethanesulfonate

CAS: 1469284-79-4

Formula: C₂₃H₃₀ClN₇O₄S

Purity: 98%

Molecular weight: 536.0468

Ref: IN-DA01ENIJ

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate

Purity: ≥98%

Molecular weight: 536.05g/mol

Ref: 54-BUP08556

PF 06424439

CAS: 1469284-79-4

PF 06424439 is a drug discovery tool for the study of ion channels. It is an antagonist of the nicotinic acetylcholine receptor (nAChR) and a partial agonist of the serotonin receptor 5-HT2B. PF 06424439 has been shown to block the activation of potassium channels in rat hippocampus, and it inhibits the proliferation of prostate cancer cells by blocking voltage-gated calcium channels. PF 06424439 binds to protein receptors in a ligand-receptor binding interaction, which can be used as a research tool in cell biology.

Formula: C₂₂H₂₆ClN₇O·CH₄O₃S

Purity: Min. 95%

Molecular weight: 536.05 g/mol

Ref: 3D-UIC28479