CAS 1469284-79-4

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate: oral, potent, selective DGAT2 inhibitor (IC50=14 nM), noncompetitive, slowly reversible.

Formula: C₂₃H₃₀ClN₇O₄S

Purity: 99.77% - 99.9%

Color and Shape: Solid

Molecular weight: 536.05

Ref: TM-T12425

(R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-1H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

CAS: 1469284-79-4

Formula: C₂₃H₃₀ClN₇O₄S

Purity: 99%

Molecular weight: 536.0468

Ref: IN-DA01ENIJ

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate

Formula: C₂₃H₃₀ClN₇O₄S

Purity: ≥98%

Molecular weight: 536.05

Ref: 54-BUP08556

PF-06424439 methanesulfonate

CAS: 1469284-79-4

(R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-1H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

Formula: C₂₃H₃₀ClN₇O₄S

Purity: 99%

Molecular weight: 536.05

Ref: IN-DG01135008

PF 06424439

CAS: 1469284-79-4

PF 06424439 is a drug discovery tool for the study of ion channels. It is an antagonist of the nicotinic acetylcholine receptor (nAChR) and a partial agonist of the serotonin receptor 5-HT2B. PF 06424439 has been shown to block the activation of potassium channels in rat hippocampus, and it inhibits the proliferation of prostate cancer cells by blocking voltage-gated calcium channels. PF 06424439 binds to protein receptors in a ligand-receptor binding interaction, which can be used as a research tool in cell biology.

Formula: C₂₂H₂₆ClN₇O·CH₄O₃S

Purity: Min. 95%

Molecular weight: 536.05 g/mol

Ref: 3D-UIC28479