CAS 147-24-0

Diphenhydramine hydrochloride

Description:

Diphenhydramine hydrochloride is an antihistamine commonly used to relieve symptoms of allergy, hay fever, and the common cold. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The chemical structure of diphenhydramine includes a diphenylmethanol moiety, contributing to its pharmacological properties. It acts primarily as an antagonist to the H1 histamine receptor, thereby reducing the effects of histamine in the body. In addition to its antihistaminic properties, diphenhydramine is also utilized as a short-term treatment for insomnia and as an adjunct in the management of motion sickness. The hydrochloride salt form enhances its solubility in water, making it suitable for various formulations, including tablets, capsules, and liquid preparations. Common side effects may include drowsiness, dizziness, dry mouth, and blurred vision. Due to its sedative properties, caution is advised when operating machinery or driving after consumption.

Formula: C₁₇H₂₁NO·ClH

InChI: InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key: InChIKey=PCHPORCSPXIHLZ-UHFFFAOYSA-N

SMILES: C(OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2.Cl

Synonyms:

• 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
• 2-(diphenylmethoxy)-N,N-dimethylethanamine
• 2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride (1:1)
• 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride
• Alledryl
• Allergan
• Allergina
• Allergival
• Amidryl
• Asdrin
• Bagodryl
• Bax
• Bena
• Bena-Fedrin
• Benadril hydrochloride
• Benadryl
• Benison
• Benocten
• Benodine
• Benylin
• Benzantin
• Benzhydramine
• Benzhydramine hydrochloride
• Benzhydrol β-dimethylaminoethyl ether hydrochloride
• Denydryl
• Dibondrin
• Difenhidramina, Clorhidrato
• Difenhydramine hydrochloride
• Dimedrol
• Dimedrol hydrochloride
• Dimedrolum
• Diphantine
• Diphenhydramine HCl
• Diphenhydramine hydrochlorids
• Diphenhydramine, Chlorhydrate
• Diphenhydraminhydrochlorid
• Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
• Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)
• Ethylamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
• Fenylhist
• Halbmond
• Histacyl
• N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
• Noctomin
• Psilo-Balsam
• Resmin
• Restamin
• S 8
• Sedopretten
• Sekundal D
• Syntedril
• Theraflu
• Vena
• Wehydryl
• [2-(Diphenylmethoxy)ethyl]dimethylamine hydrochloride

Diphenhydramine

CAS: 147-24-0, 58-73-1

Formula: C₁₇H₂₁NO

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Yellow clear liquid

Molecular weight: 255.36

Ref: 3B-D4744

Diphenhydramine Hydrochloride

CAS: 147-24-0, 58-73-1

Formula: C₁₇H₂₁NO·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White powder to crystal

Molecular weight: 291.82

Ref: 3B-D0423

Diphenhydramine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 147-24-0

Color and Shape: Single Solution

Ref: 61-AMP0490.00-01

Diphenhydramine.HCl

CAS: 147-24-0

Color and Shape: Neat

Ref: LP-DPH-1094-HC-10

Diphenhydramine Hydrochloride

CAS: 147-24-0

Color and Shape: White Solid

Ref: 61-FOR0490.00

Diphenhydramine.HCl, 1mg/ml in Methanol (as free base)

CAS: 147-24-0

Color and Shape: Single Solution

Ref: LP-DPH-1094-HC-1LM

DIPHENHYDRAMINE HYDROCHLORIDE CRS

CAS: 147-24-0

DIPHENHYDRAMINE HYDROCHLORIDE CRS

Formula: C₁₇H₂₂ClNO

Color and Shape: Crystalline Powder. White. Whitish. Powder.

Molecular weight: 291.8157

Ref: 41-D2600000

Diphenhydramine hydrochloride

CAS: 147-24-0

Diphenhydramine hydrochloride

Formula: C₁₇H₂₁NOHCl

Purity: 99.6%

Color and Shape: White To Off-White

Molecular weight: 291.13899

Ref: 47-896

Diphenhydramine Hydrochloride

CAS: 147-24-0

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₇H₂₁NO·HCl

Color and Shape: White Powder

Molecular weight: 291.13899

Ref: 45-1218005

N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₂ClNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 291.8157

Ref: IN-DA003S9A

N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride

CAS: 147-24-0

N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride

Purity: 99%+

Molecular weight: 291.82g/mol

Ref: 54-OR1013964

Diphenhydramine hydrochloride

CAS: 147-24-0

Diphenhydramine hydrochloride

Purity: ≥98%

Molecular weight: 291.82g/mol

Ref: 54-BUP17641

Diphenhydramine HCl

CAS: 147-24-0

Formula: C₁₇H₂₁NO·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 255.36 36.46

Ref: 4Z-D-087

Diphenhydramine hydrochloride

CAS: 147-24-0

DPH: antihistamine for cough, nausea, itching, allergy, Parkinson's, sleep aid, cold remedy.

Formula: C₁₇H₂₂ClNO

Purity: 99.84%

Color and Shape: Taste Ph (5% Aqueous Solution) 4-6 (Ntp 1992)

Molecular weight: 291.82

Ref: TM-T0330

Diphenhydramine Hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₁NOClH

Color and Shape: White Solid

Molecular weight: 291.82

Ref: 86-MM0490.00

Diphenhydramine hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₁NO·ClH

Color and Shape: Neat

Molecular weight: 291.82

Ref: 04-C12881000

Diphenhydramine hydrochloride 100 µg/mL in Acetonitrile

Controlled Product

CAS: 147-24-0

Formula: C₁₇H₂₁NO·ClH

Color and Shape: Single Solution

Molecular weight: 291.82

Ref: 04-A12881000AL-100

Diphenhydramine hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₁NO·HCl

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 291.82

Ref: 7W-GP7830

Diphenhydramine Hydrochloride

CAS: 147-24-0

Stability Hygroscopic
Applications Diphenhydramine is an H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic.
References Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),

Formula: C₁₇H₂₁NO·ClH

Color and Shape: White Solid

Molecular weight: 291.82

Ref: TR-D486900

Diphenhydramine hydrochloride

Controlled Product

CAS: 147-24-0

Diphenhydramine is a first-generation antihistamine that crosses the blood-brain barrier and blocks the histamine H1 receptor. It has been used in the treatment of allergic reactions and bowel disease. The drug has shown no significant adverse effects in humans at doses up to 100 mg/day. Diphenhydramine is also used as an antiemetic, for motion sickness, and for other indications. It is available over the counter and by prescription. Side effects include dry mouth, blurred vision, constipation, difficulty urinating, and sleepiness. Diphenhydramine may interact with other drugs such as fructus (fruit) of Elaeagnus angustifolia (Russian olive), which can cause a decrease in blood pressure when taken together with diphenhydramine.

Formula: C₁₇H₂₁NO•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 291.82 g/mol

Ref: 3D-FD01515

[2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₂ClNO

Purity: 98%

Molecular weight: 291.82

Ref: 10-F358131

Diphenhydramine Hydrochloride (1.0 mg/mL in Methanol)

Controlled Product

CAS: 147-24-0

Formula: C₁₇H₂₁NO·ClH

Color and Shape: Colourless

Molecular weight: 291.82

Ref: TR-KIT1205