CAS 147-94-4: Cytarabine

Description: Cytarabine, also known as cytosine arabinoside, is a nucleoside analog primarily used as an antineoplastic agent in the treatment of certain types of leukemia and lymphoma. Its chemical formula is C9H13N3O5, and it features a sugar moiety (arabinoside) linked to a cytosine base. Cytarabine is characterized by its ability to inhibit DNA synthesis, making it effective in targeting rapidly dividing cancer cells. It is typically administered via injection, as it is poorly absorbed when taken orally. The compound is known for its relatively short half-life, necessitating continuous infusion or frequent dosing in clinical settings. Common side effects include myelosuppression, which can lead to increased susceptibility to infections and bleeding, as well as gastrointestinal disturbances. Due to its mechanism of action, cytarabine is often used in combination with other chemotherapeutic agents to enhance therapeutic efficacy. Its use is carefully monitored, given the potential for significant toxicity, particularly in patients with pre-existing conditions or those receiving concurrent therapies.

Formula: C₉H₁₃N₃O₅

InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChI key: InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N

SMILES: O=C1N=C(N)C=CN1C2OC(CO)C(O)C2O

Synonyms:

• (Arabinofuranosyl)cytosine
• 1-(Arabinofuranosyl)cytosine
• 1-(β-<span class="text-smallcaps">D</span>-Arabinofuranosyl)cytosine
• 1-(β-D-Arabinofuranosyl)cytosine
• 1-b-D-Arabinofuranosylcytosine
• 1-β-<span class="text-smallcaps">D</span>-Arabinosylcytosine
• 1-β-Arabinofuranosylcytosine
• 1-β-D-Arabinosylcytosine
• 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• 2(1H)-Pyrimidinone, 4-amino-1-β-D-arabinofuranosyl-
• 4-Amino-1-Beta-D-Arabinofuranosyl-2(1H)-Pyrimidinone
• 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
• 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-2(1H)-pyrimidinone
• 4-Amino-1-β-D-Arabinofuranosyl-2(1H)-pyrimidinone
• 4-amino-1-(D-arabinofuranosyl)pyrimidin-2(1H)-one
• 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
• 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
• 4-amino-1-pentofuranosylpyrimidin-2(1H)-one
• Ac 1075
• Alexan
• Ara-C
• Ara-cell
• ArabinoFuranosylcytosine
• Arabinocytidine
• Arabinocytosine
• Arabinoside C
• Arabitin
• Aracytidine
• Aracytin
• Aracytine
• Arafcyt
• Chx 3311
• Citarabina
• Citozar
• Cyclocide
• Cylocide
• Cylocide N
• Cytarabin
• Cytarabine
• Cytarabinoside
• Cytosar
• Cytosar U
• Cytosine Arabinoside
• Cytosine β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Cytosine β-<span class="text-smallcaps">D</span>-arabinoside
• Cytosine β-D-arabinofuranoside
• Cytosine β-D-arabinoside
• Cytosine, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• Cytosine, 1-β-D-arabinofuranosyl-
• Cytosine-1-β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Cytosine-1-β-D-arabinofuranoside
• Cytosine-1-β-arabinofuranoside
• DepoCyt
• DepoCyte
• Erpalfa
• Iretin
• Mk 8242
• N-(2-oxo-2,3-dihydropyrimidin-4-yl)-D-arabinofuranosylamine
• Nsc 287459
• Nsc 63878
• Sch 900242
• Spongocytidine
• Tarabine PFS
• U 19920
• U 19920A
• Udicil
• ara-Cytosine
• Cytosine 1-beta-D-arabinofuranoside

Cytarabine

CAS: 147-94-469-74-9

• Formula: C₉H₁₃N₃O₅
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 243.22

Cytarabine RS

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Molecular weight: 243.2166

Cytarabine CRS

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Color and Shape: Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 243.2166

Cytarabine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Purity: 99.9%
• Color and Shape: White
• Molecular weight: 243.08552

Cytarabine

CAS: 147-94-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₉H₁₃N₃O₅
• Color and Shape: White Off-White Powder
• Molecular weight: 243.08552

Cytosine β-D-arabinofuranoside

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 243.2166

Cytarabine

CAS: 147-94-4

Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).

• Formula: C₉H₁₃N₃O₅
• Purity: 99.83% - 99.93%
• Color and Shape: Fine Off-White Crystalline Powder
• Molecular weight: 243.22

Cytarabine-13C-15N2

CAS: 147-94-4

• Formula: C₈₁₃CH₁₃N₁₅N₂O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 246.20

Cytarabine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Purity: 98.0 - 102.0 % (dried basis)
• Color and Shape: White crystalline powder
• Molecular weight: 243.22

Cytarabine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 243.22

Cytosine-?-D-arabinofuranoside

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Purity: 98%+
• Color and Shape: white crystalline powder
• Molecular weight: 243.22g/mol

Cytarabine

CAS: 147-94-4

• Purity: 99.91%
• Molecular weight: 243.22g/mol

Arabinocytosine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Purity: 95%~99%
• Molecular weight: 243.219

Cytarabine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Color and Shape: Neat
• Molecular weight: 243.22

Cytarabine, 98%

CAS: 147-94-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₉H₁₃N₃O₅
• Purity: 98%
• Color and Shape: White to Beige, Crystalline powder
• Molecular weight: 243.22

Cytarabine

CAS: 147-94-4

• Formula: C₉H₁₃N₃O₅
• Color and Shape: Neat
• Molecular weight: 243.22

4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

CAS: 147-94-4

• Purity: 95.0%
• Color and Shape: Solid, White to almost white powder
• Molecular weight: 243.218994140625

Cytarabine-13C3

CAS: 147-94-4

• Formula: C₆₁₃C₃H₁₃N₃O₅
• Molecular weight: 246.19

Cytarabine

CAS: 147-94-4

Applications Cytarabine is used as an antineoplastic and antiviral. It is a selective inhibitor of …

• Formula: C₉H₁₃N₃O₅
• Color and Shape: Neat
• Molecular weight: 243.22

Cytarabine-13C3

CAS: 147-94-4

Stability Hygroscopic Applications Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective …

• Formula: C₆₁₃C₃H₁₃N₃O₅
• Color and Shape: Beige
• Molecular weight: 246.19