CAS 147-94-4
:Cytarabine
Description:
Cytarabine, also known as cytosine arabinoside, is a nucleoside analog primarily used as an antineoplastic agent in the treatment of certain types of leukemia and lymphoma. Its chemical formula is C9H13N3O5, and it features a sugar moiety (arabinoside) linked to a cytosine base. Cytarabine is characterized by its ability to inhibit DNA synthesis, making it effective in targeting rapidly dividing cancer cells. It is typically administered via injection, as it is poorly absorbed when taken orally. The compound is known for its relatively short half-life, necessitating continuous infusion or frequent dosing in clinical settings. Common side effects include myelosuppression, which can lead to increased susceptibility to infections and bleeding, as well as gastrointestinal disturbances. Due to its mechanism of action, cytarabine is often used in combination with other chemotherapeutic agents to enhance therapeutic efficacy. Its use is carefully monitored, given the potential for significant toxicity, particularly in patients with pre-existing conditions or those receiving concurrent therapies.
Formula:C9H13N3O5
InChI:InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
InChI key:InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N
SMILES:O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2
Synonyms:- (Arabinofuranosyl)cytosine
- 1-(Arabinofuranosyl)cytosine
- 1-(β-<span class="text-smallcaps">D</span>-Arabinofuranosyl)cytosine
- 1-(β-D-Arabinofuranosyl)cytosine
- 1-b-D-Arabinofuranosylcytosine
- 1-β-<span class="text-smallcaps">D</span>-Arabinosylcytosine
- 1-β-Arabinofuranosylcytosine
- 1-β-D-Arabinosylcytosine
- 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- 2(1H)-Pyrimidinone, 4-amino-1-β-D-arabinofuranosyl-
- 4-Amino-1-Beta-D-Arabinofuranosyl-2(1H)-Pyrimidinone
- 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
- 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-2(1H)-pyrimidinone
- 4-Amino-1-β-D-Arabinofuranosyl-2(1H)-pyrimidinone
- 4-amino-1-(D-arabinofuranosyl)pyrimidin-2(1H)-one
- 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
- 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
- 4-amino-1-pentofuranosylpyrimidin-2(1H)-one
- Ac 1075
- Alexan
- Ara-C
- Ara-cell
- ArabinoFuranosylcytosine
- Arabinocytidine
- Arabinocytosine
- Arabinoside C
- Arabitin
- Aracytidine
- Aracytin
- Aracytine
- Arafcyt
- Chx 3311
- Citarabina
- Citozar
- Cyclocide
- Cylocide
- Cylocide N
- Cytarabin
- Cytarabine
- Cytarabinoside
- Cytosar
- Cytosar U
- Cytosine Arabinoside
- Cytosine β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Cytosine β-<span class="text-smallcaps">D</span>-arabinoside
- Cytosine β-D-arabinofuranoside
- Cytosine β-D-arabinoside
- Cytosine, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
- Cytosine, 1-β-D-arabinofuranosyl-
- Cytosine-1-β-<span class="text-smallcaps">D</span>-arabinofuranoside
- Cytosine-1-β-D-arabinofuranoside
- Cytosine-1-β-arabinofuranoside
- DepoCyt
- DepoCyte
- Erpalfa
- Iretin
- Mk 8242
- N-(2-oxo-2,3-dihydropyrimidin-4-yl)-D-arabinofuranosylamine
- Nsc 287459
- Nsc 63878
- Sch 900242
- Spongocytidine
- Tarabine PFS
- U 19920
- U 19920A
- Udicil
- ara-Cytosine
- See more synonyms
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CYTARABINE CRS
CAS:CYTARABINE CRSFormula:C9H13N3O5Color and Shape:Added ModifiedMolecular weight:243.2166Cytarabine
CAS:CytarabineFormula:C9H13N3O5Purity:99.9%Color and Shape:WhiteMolecular weight:243.08552Cytarabine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C9H13N3O5Color and Shape:White Off-White PowderMolecular weight:243.085524-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
CAS:Formula:C9H13N3O5Purity:95%Color and Shape:SolidMolecular weight:243.2166Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formula:C9H13N3O5Purity:99.83% - 99.93%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:243.22Cytarabine
CAS:Formula:C9H13N3O5Purity:98.0 - 102.0 % (dried basis)Color and Shape:White crystalline powderMolecular weight:243.22Cytosine-β-D-arabinofuranoside
CAS:Cytosine-β-D-arabinofuranosideFormula:C9H13N3O5Purity:98%Color and Shape: white crystalline powderMolecular weight:243.22g/molCytarabine-13C-15N2
CAS:Formula:C813CH13N15N2O5Color and Shape:White To Off-White SolidMolecular weight:246.20Cytarabine-13C3
CAS:Controlled ProductStability Hygroscopic
Applications Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.
References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986)Formula:C613C3H13N3O5Color and Shape:BeigeMolecular weight:246.19Cytarabine
CAS:Applications Cytarabine is used as an antineoplastic and antiviral. It is a selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.Cytarabine, or cytosine arabinoside, is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma. It is also known as Ara-C (Arabinofuranosyl Cytidine). It destroys cancer cells by interfering with DNA synthesis.
References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986);Formula:C9H13N3O5Color and Shape:NeatMolecular weight:243.22Cytarabine
CAS:Anti-viral; anti-neoplasticFormula:C9H13N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:243.22 g/mol4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
CAS:Formula:C9H13N3O5Purity:98%Color and Shape:White to almost white powderMolecular weight:243.219Cytarabine
CAS:Formula:C9H13N3O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:243.22
![4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0034OE.jpg&w=3840&q=75)
