CAS 1480-96-2

5-Fluoro-2-methoxy-4(3H)-pyrimidinone

Description:

5-Fluoro-2-methoxy-4(3H)-pyrimidinone is a chemical compound characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. The presence of a fluorine atom at the 5-position and a methoxy group (-OCH3) at the 2-position contributes to its unique chemical properties. This compound is typically a white to off-white solid and is soluble in polar organic solvents. It exhibits potential biological activity, making it of interest in pharmaceutical research, particularly in the development of antiviral and anticancer agents. The molecular structure allows for various interactions with biological targets, which can influence its pharmacokinetic and pharmacodynamic profiles. Additionally, the compound's stability and reactivity can be affected by the substituents on the pyrimidine ring, making it a subject of study in medicinal chemistry. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₅H₅FN₂O₂

InChI: InChI=1/C5H5FN2O2/c1-10-5-7-2-3(6)4(9)8-5/h2H,1H3,(H,7,8,9)

InChI key: InChIKey=VMIFBCPINLZNNI-UHFFFAOYSA-N

SMILES: O(C)C=1NC(=O)C(F)=CN1

Synonyms:

• 2-Methoxy-4-hydroxy-5-fluoropyrimidine
• 2-Methoxy-5-fluorouracil
• 4(1H)-Pyrimidinone, 5-fluoro-2-methoxy-
• 4(3H)-Pyrimidinone, 5-fluoro-2-methoxy-
• 5-Fluoro-2-methoxy-4(3H)-pyrimidinone
• 5-Fluoro-2-methoxy-pyrimidin-4-ol
• 5-Fluoro-4-hydroxy-2-methoxypyrimidine
• 5-fluoro-2-methoxypyrimidin-4(3H)-one
• NSC 527067
• 5-FLUORO-2-METHOXY-4-PYRIMIDINONE
• 2-O-METHYL-5-FLUOROURACIL
• 5-FLUORO-2-METHOXYURACIL
• 4(1H)-Pyrimidinone, 5-fluoro-2-methoxy-(9CI)
• 5-FLUORO-2-METHOXY-4(1H)PYRIMIDINONE
• 5-FLUORO-2-METHOXY-3H-PYRIMIDIN-4-ONE
• 5-FLUORO-2-METHOXY-4(1H)PYRIMIDINONE, 9&
• 2-Methoxyl-5-fluorouracil

5-Fluoro-2-methoxy-4-pyrimidinone

CAS: 1480-96-2

Formula: C₅H₅FN₂O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 144.11

Ref: 3B-F0547

5-Fluoro-2-methoxypyrimidin-4(3H)-one

CAS: 1480-96-2

Formula: C₅H₅FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 144.1038

Ref: IN-DA00349N

5-Fluoro-4-hydroxy-2-methoxypyrimidine

CAS: 1480-96-2

5-Fluoro-4-hydroxy-2-methoxypyrimidine

Purity: 98%

Color and Shape: Off-White Solid

Molecular weight: 144.10g/mol

Ref: 54-PC7302

5-Fluoro-2-methoxypyrimidin-4(3H)-one

CAS: 1480-96-2

5-Fluoro-2-methoxypyrimidin-4(3H)-one

Formula: C₅H₅FN₂O₂

Purity: ≥95%

Color and Shape: faint red to faint orange powder

Molecular weight: 144.10g/mol

Ref: 54-PC48339

Capecitabine Impurity 35

CAS: 1480-96-2

Formula: C₅H₅FN₂O₂

Molecular weight: 144.11

Ref: 4Z-C-3549

5-Fluoro-4-hydroxy-2-methoxypyrimidine

CAS: 1480-96-2

5-Fluoro-4-hydroxy-2-methoxypyrimidine (5FMMP) is a chemical intermediate that is used in the synthesis of various pharmaceuticals, including antibiotics. It can be obtained by reacting phosphorus oxychloride with activated 2-methoxybenzaldehyde. This chemical intermediate is highly reactive and has been shown to be virulent against some strains of bacteria, such as E. coli and Proteus mirabilis. 5FMMP binds to the bacterial cell wall using its primary amine group, which prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The chlorinating reaction between 5FMMP and sodium hypochlorite results in hydrochloric acid generation. This chemical intermediate can also be synthesized from recycled chemicals such as ethyl chloride or chloroform.

Formula: C₅H₅FN₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 144.1 g/mol

Ref: 3D-FF23404

2-O-Methyl-5-fluorouracil

CAS: 1480-96-2

Formula: C₅H₅FN₂O₂

Purity: 98%

Molecular weight: 144.105

Ref: 10-F036394

5-Fluoro-4-hydroxy-2-methoxypyrimidine

Controlled Product

CAS: 1480-96-2

Formula: C₅H₅FN₂O₂

Color and Shape: Neat

Molecular weight: 144.10

Ref: TR-F591775