CAS 148553-50-8: Pregabalin
Description:Pregabalin is a pharmaceutical compound primarily used as an anticonvulsant and analgesic. It is classified as a gamma-aminobutyric acid (GABA) analogue, although it does not bind to GABA receptors. Pregabalin is effective in treating neuropathic pain, generalized anxiety disorder, and as an adjunct therapy for partial seizures. Its chemical formula is C8H17NO2, and it features a 2-(2-ethylpropyl) structure with a carboxylic acid group, contributing to its solubility in water and organic solvents. Pregabalin exhibits a high bioavailability and is rapidly absorbed after oral administration, with peak plasma concentrations typically reached within a few hours. The substance is known for its relatively low potential for abuse compared to other medications in its class, although it can still lead to dependence in some individuals. Common side effects include dizziness, somnolence, and peripheral edema. Pregabalin is marketed under various brand names, including Lyrica, and is subject to regulatory control in many countries due to its therapeutic effects and potential for misuse.
Formula:C8H17NO2
InChI:InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
InChI key:InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N
SMILES:O=C(O)CC(CN)CC(C)C
- Synonyms:
- 3-(aminomethyl)-5-methyl-hexanoic acid
- (3S)-3-(aminomethyl)-5-methyl-hexanoic acid
- (R-)-3-isobutyl GABA
- Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-
- Hexanoic acid, 3-(aminomethyl)-5-methyl-, (S)-
- PD 144723
- PD 144723
- TOS-BB-0910
- 3-(aminomethyl)-5-methyl-(S)-Lyrica
- 3-(aminomethyl)-5-methyl-(3S)-Hexanoic acid
- See more synonyms
- CI 1008
- (3S)-3-(Aminomethyl)-5-methylhexanoic acid
- Pregablin
- 3-isobutyl GABA
- CI 1008
- Pregabalin intermediate
- (3R)-3-(aminomethyl)-5-methylhexanoic acid
- (S)(+)-3-Aminomethyl-5-methyl-hecanoic acid
- CI-1008
- (S)-Pregabalin
- PD-144723
- Pregabalin [USAN]
