CAS 148553-50-8

Pregabalin

Description:

Pregabalin is a pharmaceutical compound primarily used as an anticonvulsant and analgesic. It is classified as a gamma-aminobutyric acid (GABA) analogue, although it does not bind to GABA receptors. Pregabalin is effective in treating neuropathic pain, generalized anxiety disorder, and as an adjunct therapy for partial seizures. Its chemical formula is C8H17NO2, and it features a 2-(2-ethylpropyl) structure with a carboxylic acid group, contributing to its solubility in water and organic solvents. Pregabalin exhibits a high bioavailability and is rapidly absorbed after oral administration, with peak plasma concentrations typically reached within a few hours. The substance is known for its relatively low potential for abuse compared to other medications in its class, although it can still lead to dependence in some individuals. Common side effects include dizziness, somnolence, and peripheral edema. Pregabalin is marketed under various brand names, including Lyrica, and is subject to regulatory control in many countries due to its therapeutic effects and potential for misuse.

Formula: C₈H₁₇NO₂

InChI: InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1

InChI key: InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N

SMILES: [C@H](CC(C)C)(CC(O)=O)CN

Synonyms:

• 3-(aminomethyl)-5-methyl-hexanoic acid
• (3S)-3-(aminomethyl)-5-methyl-hexanoic acid
• (R-)-3-isobutyl GABA
• Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-
• Hexanoic acid, 3-(aminomethyl)-5-methyl-, (S)-
• PD 144723
• PD 144723
• TOS-BB-0910
• 3-(aminomethyl)-5-methyl-(S)-Lyrica
• 3-(aminomethyl)-5-methyl-(3S)-Hexanoic acid
• CI 1008
• (3S)-3-(Aminomethyl)-5-methylhexanoic acid
• Pregablin
• 3-isobutyl GABA
• CI 1008
• Pregabalin intermediate
• (3R)-3-(aminomethyl)-5-methylhexanoic acid
• (S)(+)-3-Aminomethyl-5-methyl-hecanoic acid
• CI-1008
• (S)-Pregabalin
• PD-144723

Pregabalin

CAS: 148553-50-8

Formula: C₈H₁₇NO₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 159.23

Ref: 3B-P2840

Pregabalin, 1mg/ml in Methanol

CAS: 148553-50-8

Color and Shape: Single Solution

Ref: LP-PRE-1475-1LM

Pregabalin

Controlled Product

CAS: 148553-50-8

Color and Shape: Neat

Ref: LP-PRE-1475-10

Pregabalin

CAS: 148553-50-8

Color and Shape: Neat

Ref: 61-FOR1376.00

PREGABALIN CRS

CAS: 148553-50-8

PREGABALIN CRS

Color and Shape: Added

Ref: 41-Y0001805

Pregabalin

CAS: 148553-50-8

Formula: C₈H₁₇NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 159.23

Ref: 4Z-P-273

Pregabalin

CAS: 148553-50-8

Color and Shape: Neat

Ref: 86-MM1376.00

Pregabalin

Controlled Product

CAS: 148553-50-8

Formula: C₈H₁₇NO₂

Color and Shape: Neat

Molecular weight: 159.23

Ref: 04-C16286600

(S)-Pregabalin-13C3

Controlled Product

CAS: 148553-50-8

Applications (S)-Pregabalin-13C3, is the labeled analogue of (S)-Pregabalin (P704790), a S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)

Formula: C₅₁₃C₃H₁₇NO₂

Color and Shape: Off-White

Molecular weight: 162.2

Ref: TR-P704793

(S)-Pregabalin

Controlled Product

CAS: 148553-50-8

Applications S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999);

Formula: C₈H₁₇NO₂

Color and Shape: Off-White

Molecular weight: 159.23

Ref: TR-P704790

Pregabalin

Controlled Product

CAS: 148553-50-8

Pregabalin is a drug that has been approved by the FDA to treat chronic pain, specifically neuropathic pain. It binds to voltage-dependent calcium channels, which are found in the central and peripheral nervous systems. Pregabalin is also used as an add-on treatment for epilepsy, anxiety disorders, and fibromyalgia. This drug has been shown to be effective against neuropathic pain in both adults and children. However, it is not recommended for treating chronic cough or bowel disease because of its potential side effects. Pregabalin can cause dizziness and drowsiness, so it should be avoided in patients who have difficulty with balance or coordination (e.g., people who have had a stroke).

Formula: C₈H₁₇NO₂

Purity: Min. 98 Area-%

Molecular weight: 159.23 g/mol

Ref: 3D-Q-201617

Pregabalin

Controlled Product

CAS: 148553-50-8

Pregabalin

Formula: C₈H₁₇NO₂

Purity: 100.0%

Color and Shape: Off-White

Molecular weight: 159.12593

Ref: 47-1264

Pregabalin impurity standard

Controlled Product

CAS: 148553-50-8

Pregabalin impurity standard

Color and Shape: Off-White

Ref: 47-1266

Pregabalin CV

Controlled Product

CAS: 148553-50-8

Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoi

Formula: C₈H₁₇NO₂

Color and Shape: Off-White Powder

Molecular weight: 159.12593

Ref: 45-1559618

Pregabalin Impurity PD0310887

CAS: 148553-50-8

Formula: C₁₄H₂₅NO₆

Color and Shape: White To Off-White Solid

Molecular weight: 303.36

Ref: 4Z-P-2735