CAS 14907-98-3

Brusatol

Description:

Brusatol, with the CAS number 14907-98-3, is a natural compound derived from the plant species *Brassica oleracea*, commonly known as cabbage. It belongs to the class of flavonoids, which are known for their diverse biological activities. Brusatol exhibits notable properties, including antioxidant and anti-inflammatory effects, making it of interest in pharmacological research. Its structure features a flavonoid backbone, which contributes to its ability to interact with various biological targets. Research has indicated that Brusatol may enhance the efficacy of certain chemotherapeutic agents, suggesting potential applications in cancer treatment. Additionally, it has been studied for its role in modulating cellular stress responses and promoting protective mechanisms in cells. The compound's solubility and stability can vary depending on the formulation and environmental conditions, which are important factors for its application in medicinal chemistry. Overall, Brusatol represents a promising area of study for its therapeutic potential and its role in enhancing the effects of other therapeutic agents.

Formula: C₂₆H₃₂O₁₁

InChI: InChI=1S/C26H32O11/c1-10(2)6-15(28)37-18-20-25-9-35-26(20,23(33)34-5)21(31)17(30)19(25)24(4)8-13(27)16(29)11(3)12(24)7-14(25)36-22(18)32/h6,12,14,17-21,29-31H,7-9H2,1-5H3/t12-,14+,17+,18+,19+,20+,21-,24-,25+,26-/m0/s1

InChI key: InChIKey=ZZZYHIMVKOHVIH-VILODJCFSA-N

SMILES: C(OC)(=O)[C@]12[C@]3([C@]4([C@@]([C@]5(C)[C@@](C[C@]4(OC(=O)[C@@H]3OC(C=C(C)C)=O)[H])(C(C)=C(O)C(=O)C5)[H])([C@@H](O)[C@@H]1O)[H])CO2)[H]

Synonyms:

• (11beta,12alpha,15beta)-13,20-Epoxy-3,11,12-trihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)-2,16-dioxopicras-3-en-21-oic acid, methyl ester
• 2H-3,11c-beta-(Epoxymethano)phenanthro(10,1-bc)pyran-3-alpha(3a-beta-H)-carboxylic acid, 1,4,5,6a-beta,7,7a-alpha,10,11,11a,11b-alpha-decahydro-8,11a-beta-dimethyl-5,10-dioxo-1-beta,2-alpha,4-beta,9-tetrahydroxy-, methyl ester, 4-(3-methylcrotonate)
• 2H-3,11cβ-(Epoxymethano)phenanthro[10,1-bc]pyran-3α(3aβH)-carboxylic acid, 1,4,5,6aβ,7,7aα,10,11,11a,11bα-decahydro-1β,2α,4β,9-tetrahydroxy-8,11aβ-dimethyl-5,10-dioxo-, methyl ester, 4-(3-methylcrotonate)
• Brn 1444847
• Crotonic acid, 3-methyl-, 4-ester with methyl 1,4,5,6aβ,7,7aα,10,11,11a,11bα-decahydro-1β,2α,4β,9-tetrahydroxy-8,11aβ-dimethyl-5,10-dioxo-2H-3,11cβ-(epoxymethano)phenanthro[10,1-bc]pyran-3α(3aβH)-carboxylate
• Methyl (11Beta,12Alpha,13Beta,15Beta)-3,11,12-Trihydroxy-15-[(3-Methylbut-2-Enoyl)Oxy]-2,16-Dioxo-13,20-Epoxypicras-3-En-21-Oate
• Methyl 13,20-epoxy-3,11,12-trihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)-2,16-dioxopicras-3-en-21-oate (11beta,12alpha,15beta)-
• Methyl 3,11,12-Trihydroxy-15-[(3-Methylbut-2-Enoyl)Oxy]-2,16-Dioxo-13,20-Epoxypicras-3-En-21-Oate
• Nsc 172924
• Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)-2,16-dioxo-, methyl ester, (11beta,12alpha,15beta)-
• Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-, methyl ester, (11β,12α,15β)-
• Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxo-, methyl ester, (11β,12α,15β)-
• Yatansin

Brusatol

CAS: 14907-98-3

Brusatol

Formula: C₂₆H₃₂O₁₁

Purity: 99.5%

Color and Shape: Solid

Molecular weight: 520.53

Ref: 54-BUP11591

Brusatol

CAS: 14907-98-3

Formula: C₂₆H₃₂O₁₁

Molecular weight: 520.53

Ref: 7W-GE2953

Brusatol

CAS: 14907-98-3

Brusatol

Formula: C₂₆H₃₂O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 520.53

Ref: 54-OR1023079

Brusatol

CAS: 14907-98-3

Formula: C₂₆H₃₂O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 520.5257

Ref: IN-DA003AGD

Brusatol

CAS: 14907-98-3

Formula: C₂₆H₃₂O₁₁

Purity: 95%~99%

Molecular weight: 520.531

Ref: BP-BP3641

Brusatol

CAS: 14907-98-3

Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.

Formula: C₂₆H₃₂O₁₁

Purity: 99.35% - 99.95%

Color and Shape: Solid

Molecular weight: 520.5257

Ref: TM-TQ0211

(+)-Brusatol

CAS: 14907-98-3

(1R,2S,3S,3aS,3a1R,4R,6aR,7aR,11aS,11bR)-Methyl 1,2,9-trihydroxy-8,11a-dimethyl-4-((3-methylbut-2-enoyl)oxy)-5,10-dioxo-2,3,3a,4,5,6a,7,7a,10,11,11a,11b-dodecahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromene-3-carboxylate

Formula: C₂₆H₃₂O₁₁

Purity: 98%

Molecular weight: 520.53

Ref: IN-DG250094

Brusatol

CAS: 14907-98-3

Inhibitor of protein synthesis and Nrf2-mediated chemoresistance

Formula: C₂₆H₃₂O₁₁

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 520.53 g/mol

Ref: 3D-FB30016

Brusatol - Bio-X ™

CAS: 14907-98-3

Brusatol is a NRF2 inhibitor that has anti-inflammatory and immunomodulatory properties. Brusatol may have anti-cancer effects and can cause apoptosis in some cancer cells. It is a plant derived natural quassinoid.

Formula: C₂₆H₃₂O₁₁

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 520.53 g/mol

Ref: 3D-BB300035