CAS 149155-45-3

CREBtide

Description:

CREBtide, with the CAS number 149155-45-3, is a synthetic peptide that is primarily used in biochemical research. It is derived from the cAMP response element-binding protein (CREB), which plays a crucial role in cellular signaling and gene expression regulation. CREBtide is characterized by its ability to mimic the action of CREB, thereby influencing various cellular processes, including neuronal plasticity and memory formation. The peptide typically exhibits high specificity for its target, allowing it to modulate signaling pathways effectively. In laboratory settings, CREBtide is often utilized to study the mechanisms of gene transcription and the effects of cAMP signaling in different biological contexts. Its stability and solubility in aqueous solutions make it suitable for various experimental applications. Overall, CREBtide serves as a valuable tool for researchers investigating the intricate relationships between signaling pathways and gene regulation in both normal and pathological states.

Formula: C73H129N29O19

InChI: InChI=1S/C73H129N29O19/c1-5-39(4)55(101-60(112)46(25-26-54(106)107)94-58(110)44(16-9-29-87-70(78)79)92-57(109)43(15-8-28-86-69(76)77)91-56(108)42(75)14-6-7-27-74)66(118)98-49(34-38(2)3)61(113)99-51(36-103)63(115)93-45(17-10-30-88-71(80)81)59(111)95-47(18-11-31-89-72(82)83)67(119)102-33-13-20-53(102)65(117)100-52(37-104)64(116)97-50(35-40-21-23-41(105)24-22-40)62(114)96-48(68(120)121)19-12-32-90-73(84)85/h21-24,38-39,42-53,55,103-105H,5-20,25-37,74-75H2,1-4H3,(H,91,108)(H,92,109)(H,93,115)(H,94,110)(H,95,111)(H,96,114)(H,97,116)(H,98,118)(H,99,113)(H,100,117)(H,101,112)(H,106,107)(H,120,121)(H4,76,77,86)(H4,78,79,87)(H4,80,81,88)(H4,82,83,89)(H4,84,85,90)/t39-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,55-/m0/s1

InChI key: QKXYCULATRFTIQ-KPXMCYQPSA-N

SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)N

Synonyms:

• Krreilsrrpsyr
• Crebtide

CREBtide

CAS: 149155-45-3

For cellular and molecular biology applications

Color and Shape: White, Lyophilized Powder

Ref: 02-J66434

CREBtide

CAS: 149155-45-3

CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).

Formula: C₇₃H₁₂₉N₂₉O₁₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 1716.99

Ref: TM-TP1876

CREBtide

CAS: 149155-45-3

Formula: C₇₃H₁₂₉N₂₉O₁₉

Purity: 98%

Molecular weight: 1716.9883

Ref: IN-DA00AXLH