Description:Sacubitril sodium is a pharmaceutical compound primarily used in the treatment of heart failure. It functions as a neprilysin inhibitor, which enhances the levels of natriuretic peptides, leading to vasodilation and diuresis. This mechanism helps to reduce the strain on the heart and improve overall cardiac function. Sacubitril sodium is typically administered in combination with valsartan, an angiotensin receptor blocker, to provide a synergistic effect in managing heart failure. The compound is characterized by its sodium salt form, which enhances its solubility and bioavailability. In terms of physical properties, sacubitril sodium is a white to off-white powder, and it is soluble in water. Its pharmacokinetics involve rapid absorption and metabolism, with a half-life that supports once or twice daily dosing. As with any medication, potential side effects may include hypotension, hyperkalemia, and renal impairment, necessitating careful monitoring during treatment. Overall, sacubitril sodium represents a significant advancement in heart failure management, improving patient outcomes through its unique mechanism of action.
We use cookies to enhance your visit. We do not include advertising.
Please see our Cookies Policy for more details or adjust your preferences in "Settings".
This is the advanced settings system for our own and third-party cookies. Here you can modify parameters that will directly affect your browsing experience on this website. If you wish you may check the list of Cookie types.
Please note that disabling cookies can cause failures in the normal operation of the web.
