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Tiludronate disodium

CAS 149845-07-8: Tiludronate disodium

Description:Tiludronate disodium is a bisphosphonate compound primarily used in the treatment of Paget's disease and other bone disorders. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. The substance is characterized by its disodium salt form, which enhances its solubility in aqueous solutions, facilitating its administration. Tiludronate disodium is typically administered orally and is known for its relatively low gastrointestinal side effects compared to other bisphosphonates. Its chemical structure features two phosphonate groups, which are essential for its biological activity, allowing it to bind to hydroxyapatite in bone tissue. The compound is generally well-tolerated, but like other bisphosphonates, it may be associated with rare adverse effects such as osteonecrosis of the jaw or atypical femoral fractures. Overall, Tiludronate disodium plays a significant role in managing conditions associated with abnormal bone metabolism, contributing to improved patient outcomes in bone health.

Formula:C7H9ClO6P2S·2Na

InChI:InChI=1S/C7H9ClO6P2S.2Na/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14;;/h1-4,7H,(H2,9,10,11)(H2,12,13,14);;

InChI key:InChIKey=CLNKSBSNCRWXKR-UHFFFAOYSA-N

SMILES:[Na].O=P(O)(O)C(SC1=CC=C(Cl)C=C1)P(=O)(O)O

  • Synonyms:
  • Disodium (4-chlorophenylthio)methylenediphosphonate
  • Disodium tiludronate
  • Disodium {[(4-Chlorophenyl)Sulfanyl]Methanediyl}Bis[Hydrogen (Phosphonate)]
  • Phosphonic acid, [[(4-chlorophenyl)thio]methylene]bis-, disodium salt
  • Phosphonic acid, [[(4-chlorophenyl)thio]methylene]bis-, sodium salt (1:2)
  • Skelid
  • Sr 41319G
  • Sr-41319B
  • Tiludronate disodium
  • [[(4-Chlorophenyl)Thio]Methylene]Biphosphonic Acid, Disodium Salt
  • See more synonyms
  • [[(4-Chlorophenyl)thio]methylene]biphosphonicAcid,DisodiumSalt,SR-41319B,Skelid
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Found 7 products.

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Disodium Tiludronate

CAS:149845-07-889987-06-4

Ref: 3B-D4167

25mg333.00 €
Estimated delivery in United States, on Thursday 20 Mar 2025
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Ref: 4Z-T-260001

5mg309.00 €
10mg496.00 €
25mg709.00 €
50mg881.00 €
100mg1,288.00 €
Estimated delivery in United States, on Friday 28 Mar 2025
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Tiludronic Acid Disodium Salt

CAS:149845-07-8

Ref: TR-T441250

50mg241.00 €
100mg315.00 €
250mg759.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
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Tiludronic Acid-d5 Disodium Salt

Controlled Product
CAS:149845-07-8

Ref: TR-T441252

1mg604.00 €
10mg4,052.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
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Tiludronic acid disodium salt

CAS:149845-07-8

Ref: 3D-FT28278

1g3,706.00 €
25mg320.00 €
100mg689.00 €
500mg1,976.00 €
Estimated delivery in United States, on Monday 21 Apr 2025
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Tiludronate disodium

CAS:149845-07-8

Ref: TM-T13159

5mg80.00 €
10mg115.00 €
25mg188.00 €
50mg283.00 €
100mg419.00 €
500mg843.00 €
Estimated delivery in United States, on Thursday 15 May 2025
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