CymitQuimica logo

CAS 152-11-4

:

Verapamil hydrochloride

Description:
Verapamil hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension, angina pectoris, and certain types of arrhythmias. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The compound works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of the vascular smooth muscle and a decrease in heart rate. This mechanism helps to lower blood pressure and reduce the workload on the heart. Verapamil hydrochloride has a relatively low bioavailability due to extensive first-pass metabolism, and its pharmacokinetics can be influenced by factors such as age, liver function, and concurrent medications. Common side effects may include dizziness, headache, and gastrointestinal disturbances. As with any medication, it is essential to use verapamil hydrochloride under medical supervision to manage potential interactions and contraindications effectively.
Formula:C27H38N2O4·ClH
InChI:InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChI key:InChIKey=DOQPXTMNIUCOSY-UHFFFAOYSA-N
SMILES:C(CCCN(CCC1=CC(OC)=C(OC)C=C1)C)(C(C)C)(C#N)C2=CC(OC)=C(OC)C=C2.Cl
Synonyms:
  • (+/-)-5-[N-(3,4-dimethoxyphenylethyl)-METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE
  • 2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-(propan-2-yl)pentanenitrile hydrochloride
  • 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-Dimethoxyphenyl)Ethyl](Methyl)Amino}-2-(Propan-2-Yl)Pentanenitrile Hydrochloride (1:1)
  • 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE
  • Akilen
  • Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-
  • Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-Benzeneacetonitrile Hydrochloride
  • Anpec
  • Apo-Verap
  • Apoacor
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.Found 24 products.