CAS 152-11-4: Verapamil hydrochloride

Description: Verapamil hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension, angina pectoris, and certain types of arrhythmias. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The compound works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of the vascular smooth muscle and a decrease in heart rate. This mechanism helps to lower blood pressure and reduce the workload on the heart. Verapamil hydrochloride has a relatively low bioavailability due to extensive first-pass metabolism, and its pharmacokinetics can be influenced by factors such as age, liver function, and concurrent medications. Common side effects may include dizziness, headache, and gastrointestinal disturbances. As with any medication, it is essential to use verapamil hydrochloride under medical supervision to manage potential interactions and contraindications effectively.

Formula: C₂₇H₃₈N₂O₄·ClH

InChI: InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H

InChI key: InChIKey=DOQPXTMNIUCOSY-UHFFFAOYSA-N

SMILES: Cl.N#CC(C1=CC=C(OC)C(OC)=C1)(CCCN(C)CCC2=CC=C(OC)C(OC)=C2)C(C)C

Synonyms:

• (+/-)-5-[N-(3,4-dimethoxyphenylethyl)-METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE
• 2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-(propan-2-yl)pentanenitrile hydrochloride
• 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-Dimethoxyphenyl)Ethyl](Methyl)Amino}-2-(Propan-2-Yl)Pentanenitrile Hydrochloride (1:1)
• 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE
• Akilen
• Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-
• Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-Benzeneacetonitrile Hydrochloride
• Anpec
• Apo-Verap
• Apoacor
• Arapamyl
• Azupamil
• Benzeneacetonitrile Hydrochloride
• Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, hydrochloride (1:1)
• Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride
• Berkatens
• Calan
• Calan SR
• Calaptin
• Calaptin 240SR
• Calaptin 80
• Cardiabeltin
• Cardiagutt
• Cardibeltin
• Caveril
• Civicor
• Civicor Retard
• Coraver
• Cordilox
• Cordilox SR
• Corpamil
• Covera HS
• Dignover
• Dilacoran
• Dilacoran HTA
• Drosteakard
• Finoptin
• Flamon
• Geangin
• Hexasoptin
• Hexasoptin Retard
• Ikacor
• Ikapress
• Iproveratril
• Iproveratril hydrochloride
• Iproveratrilhydrochloride
• Iso-Card SR
• Isoptin
• Isoptin Retard
• Isoptin SR
• Isoptin, hydrochloride
• Isoptine
• Isoptino
• Izoptin hydrochloride
• Izoptinhydrochloride
• Lekoptin Retard
• Lu 20175
• Manidon
• Manidon Retard
• NSC 272366
• NSC 657799
• Novo-Veramil
• Quasar
• Ravamil SR
• Securon
• Univer
• Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, hydrochloride
• Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride
• Vasolan
• Vasomil
• Vasopten
• Veracaps SR
• Veracim
• Veracor
• Verahexal
• Veraloc
• Veramex
• Veramil
• Verapamil HCl
• Verapin
• Verapress 240SR
• Veraptin
• Verdilac
• Verelan
• Verelan SR
• Verexamil
• Verogalid ER
• Verpal
• Vetrimil
• dl-Verapamil hydrochloride
• (+/-)-Verapamil hydrochloride
• (+/-)-Verapamil Hydrochloride

Verapamil Hydrochloride

CAS: 152-11-452-53-9

• Formula: C₂₇H₃₈N₂O₄·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 491.07

(+/-)-Verapamil hydrochloride, 99+%

CAS: 152-11-4

±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. …

• Formula: C₂₇H₃₉ClN₂O₄
• Purity: 99+%
• Molecular weight: 491.07

Verapamil hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄HCl
• Purity: 99.7%
• Color and Shape: White To Off-White
• Molecular weight: 490.25984

Verapamil hydrochloride RS

CAS: 152-11-4

• Formula: C₂₇H₃₉ClN₂O₄
• Molecular weight: 491.0626

Verapamil hydrochloride CRS

CAS: 152-11-4

Verapamil Hydrochloride

CAS: 152-11-4

Nitrile function compounds, not elsewhere specified or included

• Formula: C₂₇H₃₈N₂O₄·HCl
• Color and Shape: White Off-White Solid Crystalline Powder
• Molecular weight: 490.25984

Verapamil hydrochloride

CAS: 152-11-4

Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia …

• Formula: C₂₇H₃₉ClN₂O₄
• Purity: 98.7% - 99.98%
• Color and Shape: White To Off-White Powder
• Molecular weight: 491.06

5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxy phenyl)-2-isopropylvaleronitrile hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₉ClN₂O₄
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 491.0626

Verapamil hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄·ClH
• Purity: Tech
• Color and Shape: white solid
• Molecular weight: 491.06g/mol

Verapamil hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄·HCl
• Purity: ≥ 98.0%
• Color and Shape: White to almost white powder
• Molecular weight: 491.07

(±)-Verapamil-d3 HCl(N-methyl-d3)

CAS: 152-11-42714485-49-9

• Purity: 99 atom % D
• Color and Shape: White To Off-White Solid
• Molecular weight: 494.09

Verapamil Hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄·ClH
• Color and Shape: Neat
• Molecular weight: 491.06

(±)-Verapamil hydrochloride, 99+%

CAS: 152-11-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₇H₃₉ClN₂O₄
• Purity: 99+%
• Color and Shape: White to off-white, Powder
• Molecular weight: 491.07

Verapamil hydrochloride

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄·ClH
• Color and Shape: Neat
• Molecular weight: 491.06

Verapamil hydrochloride

CAS: 152-11-4

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 490.259835408

Verapamil HCl

CAS: 152-11-4

• Formula: C₂₇H₃₈N₂O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 454.61

Verapamil-d3 Hydrochloride

CAS: 152-11-4

Applications Verapamil-d3 Hydrochloride is the labeled analogue of Verapamil Hydrochloride (V125000), which is a calcium …

• Formula: C₂₇D₃H₃₅N₂O₄·ClH
• Color and Shape: Neat
• Molecular weight: 457.633646

Verapamil Hydrochloride

CAS: 152-11-4

Applications A calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV). Not a dangerous good if …

• Formula: C₂₇H₃₈N₂O₄·ClH
• Color and Shape: Neat
• Molecular weight: 491.06

Verapamil hydrochloride

CAS: 152-11-4

L-type calcium channel blocker

• Formula: C₂₇H₃₉ClN₂O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 491.06 g/mol

Verapamil HCl - Bio-X ™

CAS: 152-11-4

Verapamil is drug that belongs to the class of drugs known as calcium channel blockers. …

• Formula: C₂₇H₃₈N₂O₄•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 491.06 g/mol