CAS 152-58-9: 11-Deoxycortisol
Description:11-Deoxycortisol, also known as cortodoxone, is a steroid hormone that plays a significant role in the biosynthesis of corticosteroids. It is classified as a glucocorticoid and is produced in the adrenal cortex. The chemical structure of 11-Deoxycortisol features a steroid backbone, characterized by four fused carbon rings, with specific functional groups that contribute to its biological activity. It is a precursor in the synthesis of cortisol, which is crucial for regulating metabolism, immune response, and stress response in the body. The CAS number 152-58-9 uniquely identifies this compound in chemical databases. In terms of solubility, 11-Deoxycortisol is generally lipophilic, allowing it to easily cross cell membranes and exert its effects on target tissues. Its biological activity is mediated through binding to glucocorticoid receptors, influencing gene expression and cellular functions. Due to its role in the endocrine system, alterations in 11-Deoxycortisol levels can be indicative of various health conditions, including adrenal insufficiency or hyperplasia.
Formula:C21H30O4
InChI:InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1
InChI key:InChIKey=WHBHBVVOGNECLV-OBQKJFGGSA-N
SMILES:O=C1C=C2CCC3C(CCC4(C)C3CCC4(O)C(=O)CO)C2(C)CC1
- Synonyms:
- (8R,10R,13S,17R)-17-Hydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
- (8Xi,9Xi,10Xi,13Xi,14Xi)-17,21-Dihydroxypregn-4-Ene-3,20-Dione
- 11-Deoxy-17-hydrocorticosterone
- 11-Deoxy-17-hydroxycorticosterone
- 11-Deoxycortisol
- 11-Deoxycortisone
- 11-Deoxyhydrocortisone
- 11-Desoxy-17-hydroxycorticosterone
- 11-Desoxy-17α-hydroxycorticosterone
- 11-Desoxycortisol
- See more synonyms
- 11-Desoxycortisone
- 11-Desoxyhydrocortisone
- 11-Dioxycortisol
- 17,21-Dihydroxy-4-pregnene-3,20-dione
- 17,21-Dihydroxy-Pregn-4-Ene-3,20-Dione
- 17,21-Dihydroxypregn-4-en-3,20-dione
- 17,21-Dihydroxypregn-4-ene-3,20-dione
- 17,21-Dihydroxyprogesterone
- 17-Hydroxy-11-deoxycorticosterone
- 17alpha,21-Dihydroxypregn-4-ene-3,20-dione
- 17Α,21-Dihydroxypregn-4-Ene-3,20-Dione
- 17α,21-Dihydroxy-4-pregnen-3,20-dion
- 17α,21-Dihydroxy-4-pregnen-3,20-dione
- 17α,21-Dihydroxyprogesterone
- 17α-Hydroxycortexone
- 4-Pregnen-17α,21-diol-3,20-dion
- 4-Pregnen-17α,21-diol-3,20-dione
- 4-Pregnene-11β,17,21-triol-3,20-dione
- 4-Pregnene-17α, 21-diol-3,20-dione
- Compound S
- Corticosterone, 11-deoxy-17-hydroxy-
- Cortifen
- Cortisol, 11-deoxy-
- Cortisol, 11-dioxy-
- Cortodoxon
- Cortodoxona
- Cortodoxone
- Nsc 18317
- Pregn-4-ene-3,20-dione, 17,21-dihydroxy-
- Reichstein S
- Reichstein substance S
- Reichstein's Substanz S
- Reichstein's compound S
- Reichstein's substance S
- Sk&F 3050
- Skf 3050
- Substance S
- cortodoxone (INN)
- Δ4-Pregnene-17α,21-diol-3,20-dione
- Δ<sup>4</sup>-Pregnene-17α,21-diol-3,20-dione
- Cortexolone