CAS 152-58-9
:11-Deoxycortisol
Description:
11-Deoxycortisol, also known as cortodoxone, is a steroid hormone that plays a significant role in the biosynthesis of corticosteroids. It is classified as a glucocorticoid and is produced in the adrenal cortex. The chemical structure of 11-Deoxycortisol features a steroid backbone, characterized by four fused carbon rings, with specific functional groups that contribute to its biological activity. It is a precursor in the synthesis of cortisol, which is crucial for regulating metabolism, immune response, and stress response in the body. The CAS number 152-58-9 uniquely identifies this compound in chemical databases. In terms of solubility, 11-Deoxycortisol is generally lipophilic, allowing it to easily cross cell membranes and exert its effects on target tissues. Its biological activity is mediated through binding to glucocorticoid receptors, influencing gene expression and cellular functions. Due to its role in the endocrine system, alterations in 11-Deoxycortisol levels can be indicative of various health conditions, including adrenal insufficiency or hyperplasia.
Formula:C21H30O4
InChI:InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1
InChI key:InChIKey=WHBHBVVOGNECLV-OBQKJFGGSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Synonyms:- (8R,10R,13S,17R)-17-Hydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
- (8Xi,9Xi,10Xi,13Xi,14Xi)-17,21-Dihydroxypregn-4-Ene-3,20-Dione
- 11-Deoxy-17-hydrocorticosterone
- 11-Deoxy-17-hydroxycorticosterone
- 11-Deoxycortisol
- 11-Deoxycortisone
- 11-Deoxyhydrocortisone
- 11-Desoxy-17-hydroxycorticosterone
- 11-Desoxy-17α-hydroxycorticosterone
- 11-Desoxycortisol
- 11-Desoxycortisone
- 11-Desoxyhydrocortisone
- 11-Dioxycortisol
- 17,21-Dihydroxy-4-pregnene-3,20-dione
- 17,21-Dihydroxy-Pregn-4-Ene-3,20-Dione
- 17,21-Dihydroxypregn-4-en-3,20-dione
- 17,21-Dihydroxypregn-4-ene-3,20-dione
- 17,21-Dihydroxyprogesterone
- 17-Hydroxy-11-deoxycorticosterone
- 17alpha,21-Dihydroxypregn-4-ene-3,20-dione
- 17Α,21-Dihydroxypregn-4-Ene-3,20-Dione
- 17α,21-Dihydroxy-4-pregnen-3,20-dion
- 17α,21-Dihydroxy-4-pregnen-3,20-dione
- 17α,21-Dihydroxyprogesterone
- 17α-Hydroxycortexone
- 4-Pregnen-17α,21-diol-3,20-dion
- 4-Pregnen-17α,21-diol-3,20-dione
- 4-Pregnene-11β,17,21-triol-3,20-dione
- 4-Pregnene-17α, 21-diol-3,20-dione
- Compound S
- Corticosterone, 11-deoxy-17-hydroxy-
- Cortifen
- Cortisol, 11-deoxy-
- Cortisol, 11-dioxy-
- Cortodoxon
- Cortodoxona
- Cortodoxone
- Nsc 18317
- Pregn-4-ene-3,20-dione, 17,21-dihydroxy-
- Reichstein S
- Reichstein substance S
- Reichstein's Substanz S
- Reichstein's compound S
- Reichstein's substance S
- Sk&F 3050
- Skf 3050
- Substance S
- cortodoxone (INN)
- Δ4-Pregnene-17α,21-diol-3,20-dione
- Δ<sup>4</sup>-Pregnene-17α,21-diol-3,20-dione
- See more synonyms
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Cortexolone
CAS:Formula:C21H30O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:346.47Cortodoxone (17,21-Dihydroxypregn-4-ene-3,20-dione)
CAS:Adrenal cortical hormones and their derivatives nesoiFormula:C21H30O4Color and Shape:White PowderMolecular weight:346.21441Ref: IN-DA003P2I
10gTo inquire50gTo inquire250gTo inquire500gTo inquire100mg28.00€250mg34.00€1g64.00€5g201.00€25g504.00€Reichsteins substance S
CAS:Formula:C21H30O4Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:346.4617,21-Dihydroxypregn-4-ene-3,20-dione (Reichstein's Substance S)
CAS:Controlled ProductFormula:C21H30O4Color and Shape:NeatMolecular weight:346.46Cortodoxone
CAS:Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.Formula:C21H30O4Purity:99.26% - 99.87%Color and Shape:SolidMolecular weight:346.4611-Deoxy Cortisol
CAS:Impurity Hydrocortisone EP Impurity F
Applications 11-Deoxy Cortisol (Hydrocortisone EP Impurity F) is a glucocorticoid receptor binding.
References Gazdar, A., et al.: Cancer Res., 50, 5488, (1990), Bird, I., et al.: Endocrinology, 134, 2468 (1994), Auchus, R., et al.: J. Biol. Chem., 273, 3158(1998), Dardis, A., et al.: J. Endocrinol., 179, 131 (2003),Formula:C21H30O4Color and Shape:NeatMolecular weight:346.4611-Deoxy Cortisol-d7
CAS:Controlled ProductApplications Glucocorticoid receptor binding.A representative lots showed approximately 10% d8.
References Gazdar, A., et al.: Cancer Res., 50, 5488, (1990), Bird, I., et al.: Endocrinology, 134, 2468 (1994), Auchus, R., et al.: J. Biol. Chem., 273, 3158 (1998), Dardis, A., et al.: J. Endocrinol., 179, 131 (2003),Formula:C21H23D7O4Color and Shape:NeatMolecular weight:353.5
