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CAS 152-58-9

:

11-Deoxycortisol

Description:
11-Deoxycortisol, also known as cortodoxone, is a steroid hormone that plays a significant role in the biosynthesis of corticosteroids. It is classified as a glucocorticoid and is produced in the adrenal cortex. The chemical structure of 11-Deoxycortisol features a steroid backbone, characterized by four fused carbon rings, with specific functional groups that contribute to its biological activity. It is a precursor in the synthesis of cortisol, which is crucial for regulating metabolism, immune response, and stress response in the body. The CAS number 152-58-9 uniquely identifies this compound in chemical databases. In terms of solubility, 11-Deoxycortisol is generally lipophilic, allowing it to easily cross cell membranes and exert its effects on target tissues. Its biological activity is mediated through binding to glucocorticoid receptors, influencing gene expression and cellular functions. Due to its role in the endocrine system, alterations in 11-Deoxycortisol levels can be indicative of various health conditions, including adrenal insufficiency or hyperplasia.
Formula:C21H30O4
InChI:InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1
InChI key:InChIKey=WHBHBVVOGNECLV-OBQKJFGGSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Synonyms:
  • (8R,10R,13S,17R)-17-Hydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  • (8Xi,9Xi,10Xi,13Xi,14Xi)-17,21-Dihydroxypregn-4-Ene-3,20-Dione
  • 11-Deoxy-17-hydrocorticosterone
  • 11-Deoxy-17-hydroxycorticosterone
  • 11-Deoxycortisol
  • 11-Deoxycortisone
  • 11-Deoxyhydrocortisone
  • 11-Desoxy-17-hydroxycorticosterone
  • 11-Desoxy-17α-hydroxycorticosterone
  • 11-Desoxycortisol
  • See more synonyms
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products per page.Found 23 products.
  • CymitQuimica logo
    BePure
    + Info

    11-Deoxycortisol in Methanol

    CAS:
    Methanol

    Ref: BE-MU-2085XM-100

    1ml
    42.00€
  • 17,21-Dihydroxy-pregn-4-ene-3,20-dione
    Fluorochem
    + Info

    17,21-Dihydroxy-pregn-4-ene-3,20-dione

    CAS:
    Formula:C21H30O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:346.467

    Ref: 10-F242196

    25mg
    36.00€
    50mg
    38.00€
    100mg
    40.00€
    250mg
    43.00€
    1g
    85.00€
    5g
    223.00€
  • 11-Deoxy-17-hydroxycorticosterone
    Biosynth
    + Info

    11-Deoxy-17-hydroxycorticosterone

    Controlled Product
    CAS:
    11-Deoxycorticosterone (11DOC) is a naturally occurring corticosteroid that has been studied as a potential treatment for cancer. 11DOC is an antagonist of the mineralocorticoid receptor, which regulates sodium and potassium ions in the body. It also inhibits lymphocyte transformation and cell nuclei. The 11DOC-induced tumor regression was found to be due to decreased cortisol concentrations and increased corticosterone concentration in the experimental model. Increased corticosterone concentration led to cell lysis, while decreased cortisol concentration inhibited inflammatory lesion growth. Structural analysis revealed that 11DOC binds to the mineralocorticoid receptor with high affinity, but does not bind with high affinity to the glucocorticoid receptor. This suggests that 11DOC may be used for tumor treatment without negative side effects such as hair loss or increased appetite.
    Formula:C21H30O4
    Purity:Min. 98 Area-%
    Color and Shape:Powder
    Molecular weight:346.46 g/mol

    Ref: 3D-FD21045

    5g
    718.00€
    10g
    1,043.00€
    25g
    1,989.00€
    50g
    2,978.00€
    100g
    5,713.00€