CAS 152121-47-6: 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine

Description: 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine, with the CAS number 152121-47-6, is a chemical compound characterized by its complex structure that includes both imidazole and pyridine rings. This compound features a fluorophenyl group and a methylsulfinylphenyl substituent, which contribute to its unique chemical properties. The presence of the fluorine atom typically enhances the compound's lipophilicity and may influence its biological activity. The sulfinyl group can also impart distinctive reactivity and solubility characteristics. This compound is likely to exhibit interesting pharmacological properties, making it a candidate for research in medicinal chemistry. Its structural features suggest potential interactions with biological targets, which could be explored in drug development. As with many organic compounds, its stability, solubility, and reactivity will depend on environmental conditions such as pH and temperature. Overall, this compound represents a class of heterocyclic compounds that are of significant interest in both synthetic and medicinal chemistry.

Formula: C₂₁H₁₆FN₃OS

InChI: InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)

InChI key: InChIKey=CDMGBJANTYXAIV-UHFFFAOYSA-N

SMILES: O=S(C=1C=CC(=CC1)C2=NC(C=3C=CN=CC3)=C(N2)C=4C=CC(F)=CC4)C

Synonyms:

• 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
• 4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine
• Birb 203580
• Pb 203580
• Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-
• Pyridine, 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]-
• Rwj 64809
• Sb-203580

SB 203580

CAS: 152121-47-6

• Formula: C₂₁H₁₆FN₃OS
• Purity: >98.0%(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 377.44

SB 203580

CAS: 152121-47-6

• Formula: C₂₁H₁₆FN₃OS
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 377.4346

SB 203580

CAS: 152121-47-6

• Formula: C₂₁H₁₆FN₃OS
• Color and Shape: White To Off-White Solid
• Molecular weight: 377.44

SB 203580

CAS: 152121-47-6

• Formula: C₂₁H₁₆FN₃OS
• Purity: By hplc: >99% (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 377.43g/mol

Adezmapimod

CAS: 152121-47-6

Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.

• Formula: C₂₁H₁₆FN₃OS
• Purity: 99.42% - 99.87%
• Color and Shape: White Solid
• Molecular weight: 377.43

SB 203580

CAS: 152121-47-6

• Formula: C₂₁H₁₆FN₃OS
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 377.44

SB-203580

CAS: 152121-47-6

M02481 - SB-203580

• Formula: C₂₁H₁₆FN₃OS
• Purity: >98%
• Color and Shape: Solid
• Molecular weight: 377.44

SB-203580

CAS: 152121-47-6

Stability -200C Applications A pyridinyl imidazole which acts as a specific inhibitor of p38 MAP …

• Formula: C₂₁H₁₆FN₃OS
• Color and Shape: Neat
• Molecular weight: 377.43

SB 203580

CAS: 152121-47-6

Inhibitor of p38 MAPK kinase

• Formula: C₂₁H₁₆FN₃OS
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 377.44 g/mol