CAS 15308-01-7

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Description:

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide, with the CAS number 15308-01-7, is a chemical compound that belongs to the class of acetamides. It features a chloro substituent and two distinct aromatic rings, contributing to its complex structure and potential biological activity. The presence of chlorine atoms enhances its lipophilicity, which may influence its interaction with biological systems. This compound is typically characterized by its solid state at room temperature and may exhibit moderate solubility in organic solvents. Its molecular structure suggests potential applications in pharmaceuticals, particularly as an intermediate in the synthesis of biologically active compounds. Additionally, the presence of multiple chlorine atoms may impart specific reactivity and stability characteristics, making it of interest in various chemical research fields. Safety data should be consulted for handling and exposure risks, as halogenated compounds can exhibit toxicity and environmental persistence. Overall, 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is a notable compound for further investigation in medicinal chemistry and related disciplines.

Formula: C₁₄H₁₀Cl₃NO

InChI: InChI=1S/C14H10Cl3NO/c15-9-13(19)18(10-5-2-1-3-6-10)14-11(16)7-4-8-12(14)17/h1-8H,9H2

InChI key: InChIKey=BPEUHDIEZQWRGC-UHFFFAOYSA-N

SMILES: N(C(CCl)=O)(C1=C(Cl)C=CC=C1Cl)C2=CC=CC=C2

Synonyms:

• 2,2′,6′-Trichloro-N-phenylacetanilide
• Acetamide, 2-chloro-N-(2,6-dichlorophenyl)-N-phenyl-
• Acetanilide, 2,2′,6′-trichloro-N-phenyl-
• N-(2,6-2 Chlorophenyl)-N-phenyl-Chloroacetamide
• N-(Chloroacetyl)-2,6-dichlorodiphenylamine
• 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Acetamide, 2-chloro-N-(2,6-dichlorophenyl)-N-phenyl-

CAS: 15308-01-7

Formula: C₁₄H₁₀Cl₃NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 314.5943

Ref: IN-DA00HY3S

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

CAS: 15308-01-7

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Purity: 97%

Molecular weight: 314.59g/mol

Ref: 54-OR1002086

Diclofenac Related Compound 8

CAS: 15308-01-7

Formula: C₁₄H₁₀Cl₃NO

Color and Shape: Off-White Solid

Molecular weight: 314.59

Ref: 4Z-D-0617

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Controlled Product

CAS: 15308-01-7

Formula: C₁₄H₁₀Cl₃NO

Color and Shape: Neat

Molecular weight: 314.59

Ref: 86-MM0006.19

Diclofenac Chloroacetyl Impurity

CAS: 15308-01-7

Formula: C₁₄H₁₀Cl₃NO

Molecular weight: 314.59

Ref: ST-EA-CP-D20021

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Controlled Product

CAS: 15308-01-7

Impurity Diclofenac Impurity
Applications 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is used as a reactant in the preparation of 1-(2,6-dichlorophenyl)-3-methylene-1,3-dihydro-indol-2-one derivatives with in vitro cytotoxic activity on SW620 colon cancer cell lines.
References Virsodia, V., et. al.: Eur. J. Med. Chem., 44, 1355 (2009)

Formula: C₁₄H₁₀Cl₃NO

Color and Shape: White

Molecular weight: 314.59

Ref: TR-C377620

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

CAS: 15308-01-7

Formula: C₁₄H₁₀Cl₃NO

Purity: 97%

Color and Shape: No data available.

Molecular weight: 314.59

Ref: 10-F239226

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide-13C6

Controlled Product

CAS: 15308-01-7

Applications 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide-13C6 is an intermediate in the synthesis of Diclofenac-13C6 (D436449). Diclofenac-13C6 is a labelled analogue of Diclofenac Acid (D436465), which is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor. Diclofenac-13C6 is also an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).
References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

Formula: C₆C₈H₁₀Cl₃NO

Color and Shape: Neat

Molecular weight: 320.55

Ref: TR-C377626