CAS 153130-59-7

AD-mix-a

CAS: 153130-59-7

Formula: C₅₅H₆₆FeK₅N₁₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 1258.5252

Ref: IN-DA01CBHA

AD-mix-α

CAS: 153130-59-7

AD-mix-α

Purity: 98%

Ref: 54-OR1029959

AD-mix-α

CAS: 153130-59-7

Purity: (DHQ)2PHAL:5.52g/kg(contains <1%H2O)

Molecular weight: 1260.295

Ref: 10-F554975

AD-mix-α (Technical Grade)

Controlled Product

CAS: 153130-59-7

Applications AD-mix-α is a reagent used for Sharpless Asymmetric Dihydroxylation reactions.
References Ren, J., et al.: J. Org. Chem., 79, 6987 (2014)

Formula: C₄₈H₅₄N₆O₄·x(K₂CO₃)·x(K₂OsO₄·2H₂O)·x(K₃Fe(CN)₆

Color and Shape: Neat

Ref: TR-A200000

AD-mix-alpha

CAS: 153130-59-7

AD-mix-alpha is a drug candidate that is being developed to treat hypertension. It is an inhibitor of the enzyme DNA gyrase, which plays an important role in the regulation of bacterial cell division and DNA replication. AD-mix-alpha has been shown to be effective against Pseudomonas aeruginosa and other Gram-negative bacteria. This drug is enantiopure, meaning it contains only one form of the molecule, and therefore does not produce any stereoisomers or diastereomers as byproducts. AD-mix-alpha has been shown to have kinetic and functional properties that are similar to those of glycopeptide antibiotics such as vancomycin. The molecular modeling studies suggest that AD-mix alpha binds to the active site on gyrase through hydrogen bonding interactions with His57, Glu82, Lys87, Asp309, Ser310, and Tyr291. These interactions are similar to those observed for vancomycin. Furthermore,

Formula: C₄₈H₅₄N₆O₄•(K₂CO₃)x•(K₂OsO₄•2H₂O)x•(K₃Fe(CN)₆x

Color and Shape: Yellow Powder

Ref: 3D-FM46539