CAS 15318-45-3: thiamphenicol

Description: Thiamphenicol is a broad-spectrum antibiotic belonging to the phenicol class of antibiotics, primarily used for its antibacterial properties. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating infections caused by these microorganisms. Thiamphenicol works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the growth and reproduction of bacteria. This compound is often utilized in veterinary medicine and has applications in human medicine, particularly in cases where other antibiotics may be ineffective or contraindicated. Thiamphenicol is known for its ability to penetrate tissues and achieve therapeutic concentrations, which is advantageous in treating systemic infections. However, its use is associated with potential side effects, including bone marrow suppression and the risk of aplastic anemia, leading to restrictions in some regions. The substance is typically administered orally or via injection, and its pharmacokinetics can vary based on the route of administration. Overall, thiamphenicol is a valuable antibiotic with specific applications and considerations in clinical practice.

Formula: C₁₂H₁₅Cl₂NO₅S

InChI: InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

InChI key: InChIKey=OTVAEFIXJLOWRX-NXEZZACHSA-N

SMILES: O=C(NC(CO)C(O)C1=CC=C(C=C1)S(=O)(=O)C)C(Cl)Cl

Synonyms:

• (2′R,3′R)-Thiamphenicol
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 8065Cb
• <span class="text-smallcaps">D</span>-Thiocymetin
• <span class="text-smallcaps">D</span>-Thiophenicol
• <span class="text-smallcaps">D</span>-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
• <span class="text-smallcaps">D</span>-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,R*)]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, <span class="text-smallcaps">D</span>-threo-(+)-
• Dextrosulphenidol
• Methylsulfonyl chloramphenicol
• NSC 522822
• Thiocymetin
• Thiophenicol
• Tirsan
• Win 5063-2
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)-

Thiamphenicol

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 356.21

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in …

• Formula: C₁₂H₁₅Cl₂NO₅S
• Color and Shape: White to yellow, Powder or crystals or crystalline powder
• Molecular weight: 356.21

Thiamphenicol CRS

CAS: 15318-45-3

• Formula: C₂₇H₂₉NO₁₁
• Color and Shape: Fine Cristalline Powder. Crystals. White. Light Yellow. Powder.
• Molecular weight: 543.5193

Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 356.2222

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: 99.08%
• Color and Shape: Off-White Solid
• Molecular weight: 356.22

Thiamphenicol

CAS: 15318-45-3

• Molecular weight: 356.22g/mol

Thiamphenicol-d3

CAS: 15318-45-3

• Formula: C₁₂H₁₂D₃Cl₂NO₅S
• Color and Shape: Off-White Solid
• Molecular weight: 359.23

Thiamphenicol

CAS: 15318-45-3

• Purity: ≥98%
• Molecular weight: 356.22g/mol

Thiamphenicol

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Molecular weight: 356.23

Thiamphenicol

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: 98.0 - 102.0 % (anhydrous basis)
• Color and Shape: White to off-white powder
• Molecular weight: 356.22

Thiamphenicol, EP grade

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: 98.0 - 100.5 % (dried basis)
• Color and Shape: White to light-yellow crystalline powder
• Molecular weight: 356.22

Thiamphenicol

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Color and Shape: Neat
• Molecular weight: 356.22

Thiamphenicol

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Color and Shape: Neat
• Molecular weight: 356.22

Thiamphenicol 1000 µg/mL in Acetonitrile

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Color and Shape: Single Solution
• Molecular weight: 356.22

Thiamphenicol, 98%

CAS: 15318-45-3

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: 98%
• Color and Shape: White to off-white, Powder
• Molecular weight: 356.21

Thiamphenicol-methyl-d3

CAS: 15318-45-3

Applications Labelled Thiamphenicol (T344160). Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol …

• Formula: C₁₂H₁₂D₃Cl₂NO₅S
• Color and Shape: White To Off-White
• Molecular weight: 359.23

Thiamphenicol

CAS: 15318-45-3

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 356.2099914550781

Thiamphenicol

CAS: 15318-45-3

Applications Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a …

• Formula: C₁₂H₁₅Cl₂NO₅S
• Color and Shape: White To Yellow
• Molecular weight: 356.22

Thiamphenicol (TMP), 98%

CAS: 15318-45-3

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: min. 98%
• Color and Shape: White to off white, Crystalline powder
• Molecular weight: 356.22

Thiamphenicol

CAS: 15318-45-3

Please enquire for more information about Thiamphenicol including the price, delivery time and more detailed …

• Formula: C₁₂H₁₅Cl₂NO₅S
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 356.22 g/mol