CAS 15318-45-3
:thiamphenicol
Description:
Thiamphenicol is a broad-spectrum antibiotic belonging to the phenicol class of antibiotics, primarily used for its antibacterial properties. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating infections caused by these microorganisms. Thiamphenicol works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the growth and reproduction of bacteria. This compound is often utilized in veterinary medicine and has applications in human medicine, particularly in cases where other antibiotics may be ineffective or contraindicated. Thiamphenicol is known for its ability to penetrate tissues and achieve therapeutic concentrations, which is advantageous in treating systemic infections. However, its use is associated with potential side effects, including bone marrow suppression and the risk of aplastic anemia, leading to restrictions in some regions. The substance is typically administered orally or via injection, and its pharmacokinetics can vary based on the route of administration. Overall, thiamphenicol is a valuable antibiotic with specific applications and considerations in clinical practice.
Formula:C12H15Cl2NO5S
InChI:InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
InChI key:InChIKey=OTVAEFIXJLOWRX-NXEZZACHSA-N
SMILES:[C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(S(C)(=O)=O)C=C1
Synonyms:- (2′R,3′R)-Thiamphenicol
- 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
- 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
- 8065Cb
- <span class="text-smallcaps">D</span>-Thiocymetin
- <span class="text-smallcaps">D</span>-Thiophenicol
- <span class="text-smallcaps">D</span>-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
- <span class="text-smallcaps">D</span>-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
- Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
- Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,R*)]-
- Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, <span class="text-smallcaps">D</span>-threo-(+)-
- Dextrosulphenidol
- Methylsulfonyl chloramphenicol
- NSC 522822
- Thiocymetin
- Thiophenicol
- Tirsan
- Win 5063-2
- Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)-
- D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-P-(METHYL-SULFONYL)PHENETHYL]ACETAMIDE
- 98.0-100.5% (Assay)
- ThiocyMetin, Thiophenicol, Win 5062-2, NSC 522822
- D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
- Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)- (8CI)
- Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]- (9CI)
- D-Thiophenicol
- D-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-[HYDROXYMETHYL]-4-[METHYLSULFONYL]PHENETHYL)ACETAMIDE
- 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
- Acetamide, 2,2-dichloro-N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-4-(methylsulfonyl)phenylethyl-
- 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulfonylphenyl)ethyl]acetamide
- D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
- acetamide,2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl
- D-threo-2,2-Dichloro-N-(b-hydroxy-a-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
- D-Thiocymetin
- 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide
- Thiamphenicol,D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
- d-threo-2,2-dichloro-n-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
- THIAMPHENICOL
- 8065c.b.
- 2,2-Dichloro-N[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulphonylphenyl)-acetamide
- ThiaMphenicol API
- ThiaMphenicol / Methylsulfonyl chloraMphenicol
- ThiamphenicolBP,
- Neomyson
- (+)-2,2-Dichloro-N-[(αR,βR)-β-hydroxy-α-(hydroxymethyl)-4-(methylsulfonyl)phenethyl]acetamide
- THIAMPHENICHOL
- See more synonyms
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Found 19 products.
Thiamphenicol
CAS:Formula:C12H15Cl2NO5SPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:356.21Thiamphenicol
CAS:<p>The methyl-sulfonyl analogue of chloramphenicol</p>Formula:C12H15Cl2NO5SColor and Shape:White to yellow, Powder or crystals or crystalline powderMolecular weight:356.21THIAMPHENICOL CRS
CAS:<p>THIAMPHENICOL CRS</p>Formula:C27H29NO11Color and Shape:Fine Cristalline Powder. Crystals. White. Light Yellow. Powder.Molecular weight:543.51932,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide
CAS:Formula:C12H15Cl2NO5SPurity:98%Color and Shape:SolidMolecular weight:356.2222Thiamphenicol
CAS:<p>Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.</p>Formula:C12H15Cl2NO5SPurity:99.08% - 99.8%Color and Shape:Off-White SolidMolecular weight:356.22Thiamphenicol
CAS:Formula:C12H15Cl2NO5SPurity:98.0 - 102.0 % (anhydrous basis)Color and Shape:White to off-white powderMolecular weight:356.22Thiamphenicol, EP grade
CAS:Formula:C12H15Cl2NO5SPurity:98.0 - 100.5 % (dried basis)Color and Shape:White to light-yellow crystalline powderMolecular weight:356.22Thiamphenicol 1000 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C12H15Cl2NO5SColor and Shape:Single SolutionMolecular weight:356.22Thiamphenicol
CAS:Controlled Product<p>Applications Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.<br>References Tikhonova, E., et al.: J. Biol. Chem., 279, 32116 (2004), Baucheron, S., et al.: J. Antimicrob. Chemother., 55, 707 (2005), Pages, J., et al.: Trends. Mol. Med., 11, 382 (2005), Lomovskaya, O., et al.: Biochem. Pharmacol., 71, 910 (2006), Samosorn, S., et al.: Bioorg. Med. Chem., 14, 857 (2006),<br></p>Formula:C12H15Cl2NO5SColor and Shape:White To YellowMolecular weight:356.22Thiamphenicol-methyl-d3
CAS:Controlled Product<p>Applications Labelled Thiamphenicol (T344160). Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.<br>References Tikhonova, E., et al.: J. Biol. Chem., 279, 32116 (2004), Baucheron, S., et al.: J. Antimicrob. Chemother., 55, 707 (2005), Pages, J., et al.: Trends. Mol. Med., 11, 382 (2005), Lomovskaya, O., et al.: Biochem. Pharmacol., 71, 910 (2006), Samosorn, S., et al.: Bioorg. Med. Chem., 14, 857 (2006),<br></p>Formula:C12H12D3Cl2NO5SColor and Shape:White To Off-WhiteMolecular weight:359.23Thiamphenicol (TMP), 98%
CAS:Formula:C12H15Cl2NO5SPurity:min. 98%Color and Shape:White to off white, Crystalline powderMolecular weight:356.22Thiamphenicol
CAS:<p>Thiamphenicol is a semisynthetic derivative of chloramphenicol with action on bacterial protein synthesis inhibition and is used for treating bacterial infections, particularly in veterinary medicine.</p>Formula:C12H15Cl2NO5SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:356.22 g/mol
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