CAS 153381-95-4

XJ735

Description:

XJ735, with the CAS number 153381-95-4, is a chemical compound that has garnered attention in various research contexts, particularly in the field of medicinal chemistry. While specific characteristics such as its molecular structure, physical properties, and biological activity may vary, compounds like XJ735 are often evaluated for their potential therapeutic applications. Typically, such substances may exhibit unique solubility profiles, stability under different conditions, and specific interactions with biological targets, which are crucial for their efficacy and safety in pharmaceutical development. Additionally, the compound may undergo extensive characterization through techniques such as NMR spectroscopy, mass spectrometry, and chromatography to ascertain its purity and confirm its identity. Understanding the characteristics of XJ735 is essential for researchers aiming to explore its potential uses, whether in drug formulation or as a research tool in biochemical studies. For detailed and specific information, consulting scientific literature or databases would provide insights into its precise properties and applications.

Formula: C₂₅H₃₃F₃N₈O₉

Synonyms:

• Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Tfa
• Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Trifluoroacetate Salt
• Xj735 Trifluoroacetate Salt
• Cyclo(Ala-Arg-Gly-Asp-3-Aminomethyl-*Benzoyl)Triflu
• Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

Cyclo(Ala-Arg-Gly-Asp-Mamb)

CAS: 153381-95-4

Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1].

Formula: C₂₃H₃₂N₈O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 532.55

Ref: TM-T80075

Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)

CAS: 153381-95-4

The small molecule RGD peptidomimetic αvβ3 integrin antagonist XJ-735 contains both anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. The IC₅₀ values of XJ 735 for αvβ3-mediated inhibition of human and porcine cell adhesion, and vascular smooth muscle cell migration, ranged from 0.6 to 4.4 µM. In contrast, IC₅₀ for porcine or human αIIb/β3, α4β1, αvβ5, and α5β1 inhibition exceeded 100 µM.

Formula: C₂₃H₃₂N₈O₇

Purity: 97.2%

Molecular weight: 532.56

Ref: 01-4029366