CAS 15345-89-8

Desmethoxyyangonin

Description:

Desmethoxyyangonin is a chemical compound classified as a natural product, specifically a type of flavonoid. It is derived from the plant species *Piper methysticum*, commonly known as kava. This compound is known for its potential psychoactive properties, which are attributed to its interaction with the central nervous system. Desmethoxyyangonin exhibits a range of biological activities, including anxiolytic and sedative effects, making it of interest in both traditional medicine and modern pharmacological research. The molecular structure of desmethoxyyangonin features a characteristic flavonoid backbone, which contributes to its reactivity and interaction with various biological targets. Additionally, it is soluble in organic solvents, which facilitates its extraction from plant materials. Research into desmethoxyyangonin continues to explore its therapeutic potential, safety profile, and mechanisms of action, particularly in relation to anxiety and stress-related disorders. As with many natural compounds, further studies are necessary to fully understand its pharmacokinetics and long-term effects.

Formula: C₁₄H₁₂O₃

InChI: InChI=1/C14H12O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-10H,1H3/b8-7+

InChI key: InChIKey=DKKJNZYHGRUXBS-BQYQJAHWSA-N

SMILES: C(=C/C1=CC=CC=C1)\C2=CC(OC)=CC(=O)O2

Synonyms:

• 2H-Pyran-2-one, 4-methoxy-6-(2-phenylethenyl)-, (E)-
• 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-phenylethenyl]-
• 2H-Pyran-2-one, 4-methoxy-6-styryl-, (E)-
• 2H-pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethyl)-
• 4-Methoxy-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one
• 4-Methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one
• 4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
• 5,6-Dehydrokavain
• 5,6-Dehydrokawain
• 5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one
• Desmethoxyyangonin
• Dihydrokawain
• NSC 112161
• NSC 68686
• Yangonin, demethoxy-
• trans-5,6-Dehydrokawain
• 4-methoxy-6-[(E)-2-phenylethenyl]-2-pyranone
• MARINDININ
• DEHYDROKAWAIN
• (E)-4-Methoxy-6-styryl-2H-pyran-2-one
• 4-Methoxy-6-[(E)-2-phenylvinyl]-2H-pyran-2-one
• Demrthoxyyanggonin
• DESMETHOXYYANGONINE hplc
• Desmethoxyyangonin (Demethoxyyangonin
• 7,8-DIHYDROKAWAIN
• DESMETHOXYYANGONINE
• Desmethoxyyangonin, 98%, from Alpinia japonica (Thunb.) Miq.
• 4-methoxy-6-styryl-2h-pyran-2-one
• Ncgc00091904-01
• (e)-2h-pyran-2-on
• 4-Methoxy-6-[(1E)-2-phenylethenyl]-
• demethoxyyangonin

2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-phenylethenyl]-

CAS: 15345-89-8

Formula: C₁₄H₁₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 228.2433

Ref: IN-DA002TL6

Demethoxyyangonin

CAS: 15345-89-8

Formula: C₁₄H₁₂O₃

Molecular weight: 228.25

Ref: 7W-GY8423

Desmethoxyyangonin

CAS: 15345-89-8

Desmethoxyyangonin

Purity: ≥98%

Molecular weight: 228.24g/mol

Ref: 54-BUP08949

Demethoxyyangonin

CAS: 15345-89-8

Desmethoxyyangonin is a reversible inhibitor of MAO-B, it may have important therapeutic value for treatment of neurodegenerative disorders and Parkinson's Disease. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.

Formula: C₁₄H₁₂O₃

Purity: 95%~99%

Molecular weight: 228.247

Ref: BP-BP0474

Desmethoxyyangonin

CAS: 15345-89-8

Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.

Formula: C₁₄H₁₂O₃

Purity: 99.29% - 99.61%

Color and Shape: White To Faint Yellow Powder

Molecular weight: 228.24

Ref: TM-T5S0734

Desmethoxy Yangonin

CAS: 15345-89-8

Formula: C₁₄H₁₂O₃

Molecular weight: 228.25

Ref: 4Z-Y-007002

Desmethoxyyangonin

CAS: 15345-89-8

Lactone

Formula: C₁₄H₁₂O₃

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 228.25

Ref: 5G-89184

DEMETHOXYYANGONIN

CAS: 15345-89-8

Purity: 98%

Molecular weight: 228.246994

Ref: 10-F795516

Desmethoxy Yangonin

Controlled Product

CAS: 15345-89-8

Applications The microsomal metabolite of Yangonin (Y100550).
References Johnson, B., et al.: Chem. Res. Toxicol., 16, 733 (2003), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Zou, L., et al.: Planta Medica, 71, 142 (2005),

Formula: C₁₄H₁₂O₃

Color and Shape: Neat

Molecular weight: 228.24

Ref: TR-D290670

Desmethoxy Yangonin-d3

Controlled Product

CAS: 15345-89-8

Formula: C₁₅D₃H₁₃O₃

Color and Shape: Neat

Molecular weight: 247.304

Ref: TR-D290672

Desmethoxy yangonin

CAS: 15345-89-8

Desmethoxy yangonin is a bioactive compound, classified as a kavalactone, which is sourced from the kava plant (Piper methysticum). This compound is primarily found in the roots of the plant and is one of several kavalactones responsible for the psychoactive properties of kava. Desmethoxy yangonin interacts with the central nervous system, mainly by modulating GABA receptors, which are pivotal in mediating inhibitory neurotransmission. It also influences certain dopaminergic pathways, suggesting a unique mechanism of action that could explain its anxiolytic and mood-enhancing effects.

Formula: C₁₄H₁₂O₃

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 228.24 g/mol

Ref: 3D-FD21220