CAS 154-93-8: carmustine
Description:Carmustine, with the CAS number 154-93-8, is a potent alkylating agent primarily used in cancer chemotherapy. It belongs to the class of nitrosoureas, which are characterized by their ability to cross the blood-brain barrier, making them effective for treating brain tumors and certain other malignancies. Carmustine is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its mechanism of action involves the formation of DNA cross-links, which inhibits DNA replication and transcription, ultimately leading to cell death. Carmustine is typically administered intravenously and can be associated with various side effects, including myelosuppression, nausea, and potential long-term effects such as pulmonary toxicity. Due to its reactivity and potential for causing secondary malignancies, careful handling and monitoring are essential during its use. Overall, carmustine remains a critical component in the treatment regimens for specific cancers, particularly in cases where other therapies may be less effective.
Formula:C5H9Cl2N3O2
InChI:InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
InChI key:InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N
SMILES:O=NN(C(=O)NCCCl)CCCl
- Synonyms:
- 1,3-Bis(2-Chloroethyl)-1-Nitroso-Urea
- 1,3-Bis(2-chlorethyl)-1-nitrosourea
- 1,3-Bis(2-chloroethyl)-1-nitrosourea
- 1,3-Bis(2-chloroethyl)nitrosourea
- 1,3-Bis(β-chloroethyl)-1-nitrosourea
- Bcnu
- Becenum
- Becenun
- BiCNU
- Carmubris
- See more synonyms
- Carmustin
- Carmustina
- Dti 015
- Fda 0345
- Gliadel
- Gliadel Wafer
- N,N'-Bis(2-chloroethyl)-N-nitrosourea
- Nitrumon
- Nsc 409962
- Sk 27702
- Sri 1720
- Urea, 1,3-bis(2-chloroethyl)-1-nitroso-
- Urea, N,N'-bis(2-chloroethyl)-N'-nitroso-
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Carmustine
Ref: 3B-C2634
100mg | 142.00 € |
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Ref: 41-Y0002128
60mg | 115.00 € |
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Carmustine
Ref: 45-1096724
75mg | 471.00 € |
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1,3-Bis(2-chloroethyl)nitrosourea
Ref: IN-DA003DHD
1g | 111.00 € | ||
5g | 204.00 € | ||
25g | 577.00 € | ||
25mg | 37.00 € | ||
100mg | 54.00 € | ||
250mg | 65.00 € |
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Ref: 4Z-C-474001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
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Carmustine
Ref: 7W-GP1721
Undefined size | To inquire |
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Carmustine
Ref: TM-T3091
10mg | 48.00 € | ||
25mg | 57.00 € | ||
50mg | 70.00 € | ||
100mg | 106.00 € | ||
200mg | 165.00 € | ||
500mg | 283.00 € |
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Carmustine
Controlled ProductRef: TR-C183875
1g | 343.00 € | ||
5g | 564.00 € | ||
250mg | 193.00 € |
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Carmustine - Bio-X ™
Ref: 3D-BC164289
10mg | 147.00 € |
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Carmustine
Ref: 3D-FC19817
1g | 645.00 € | ||
2g | 1,047.00 € | ||
5g | 1,928.00 € | ||
250mg | 350.00 € | ||
500mg | 437.00 € |
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1,3-Bis(2-chloroethyl-d4)-1-nitrosourea
Controlled ProductRef: TR-C183877
10mg | 700.00 € |
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Carmustine
Ref: 4Z-A-236001
10mg | Discontinued | Request information | |
25mg | Discontinued | Request information | |
50mg | Discontinued | Request information | |
100mg | Discontinued | Request information |